Institute of Pharmacy/Pharmacognosy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria.
Photochem Photobiol Sci. 2021 Apr;20(4):475-488. doi: 10.1007/s43630-021-00034-w. Epub 2021 Mar 18.
The well-known photosensitizers hypericin, harmane, and emodin are typical pigments of certain mushroom species-is this a coincidence or an indication towards a photoactivated defense mechanism in the phylum Basidiomycota? This perspective article explores this hypothesis by cross-linking the chemistry of fungal pigments with structural requirements from known photosensitizers and insights from photoactivated strategies in the kingdom Plantae. Thereby, light is shed on a yet unexplored playground dealing with ecological questions, photopharmaceutical opportunities, and biotechnological potentials.
众所周知的光敏剂金丝桃素、哈尔满和大黄素是某些蘑菇物种的典型色素——这是巧合还是担子菌门中存在光激活防御机制的迹象？本文通过将真菌色素的化学性质与已知光敏剂的结构要求以及植物界中光激活策略的见解联系起来，探讨了这一假说。从而为一个尚未探索的领域提供了启示，涉及生态问题、光药机会和生物技术潜力。
