National Cancer Registry Ireland, Cork Airport Business Park, Cork, Ireland.
BJOG. 2014 Oct;121(11):1421-9. doi: 10.1111/1471-0528.12741. Epub 2014 Apr 1.
To explore emotional responses, and predictors of negative reactions, among women undergoing human papillomavirus (HPV) tests in routine clinical practice.
Exploratory qualitative interview study.
A large busy colposcopy clinic in a Dublin hospital.
Twenty-seven women who had had an HPV DNA test in the previous 6 months following one or more low-grade cytology tests or treatment for cervical intraepithelial neoplasia (CIN).
In-depth semi-structured interviews were conducted. Interview transcripts were analysed using a thematic approach (Framework Analysis).
Women's emotional responses and predictors of negative emotional reactions.
For most women, having a test for high-risk HPV types generated little negative or positive emotional impact. Adverse emotional responses related to HPV infection rather than testing. Factors that influenced whether women experienced negative emotional responses were: concerns over abnormal cytology or diagnosis of CIN; HPV knowledge; awareness of HPV being sexually transmitted; awareness of HPV prevalence; and HPV information needs. Women's concerns about abnormal cytology/CIN dominated all other issues.
These qualitative data suggest that in the context of follow up of abnormal cytology or treatment for CIN, the emotional impact of HPV testing may be modest: women's primary concerns at this time relate to abnormal cytology/CIN.
探讨在常规临床实践中进行人乳头瘤病毒（HPV）检测的女性的情绪反应和负面反应的预测因素。
探索性定性访谈研究。
都柏林一家大医院的繁忙阴道镜检查诊所。
27 名女性在过去 6 个月内进行了 HPV DNA 检测，此前曾进行过一次或多次低级别细胞学检查或治疗宫颈上皮内瘤变（CIN）。
进行深入的半结构化访谈。使用主题方法（框架分析）分析访谈记录。
女性的情绪反应和负面情绪反应的预测因素。
对于大多数女性来说，进行高危 HPV 类型检测几乎不会产生负面或正面的情绪影响。不良的情绪反应与 HPV 感染有关，而不是与检测有关。影响女性是否出现负面情绪反应的因素包括：对异常细胞学或 CIN 诊断的担忧；HPV 知识；对 HPV 经性传播的认识；对 HPV 流行率的认识；以及 HPV 信息需求。女性对异常细胞学/CIN 的担忧主导了所有其他问题。
这些定性数据表明，在异常细胞学或 CIN 治疗的随访背景下，HPV 检测的情绪影响可能是适度的：此时女性的主要关注点与异常细胞学/CIN 有关。
