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从鲍曼不动杆菌LAC-4菌株中分离出的多糖的结构。

The structure of the polysaccharide isolated from Acinetobacter baumannii strain LAC-4.

作者信息

Vinogradov Evgeny, Maclean Leann, Xu H Howard, Chen Wangxue

机构信息

Human Health Therapeutics Portfolio, National Research Council Canada, 100 Sussex Drive, Ottawa, Ontario K1A 0R6, Canada.

Department of Biological Sciences, California State University, 5151 State University Dr., Los Angeles, CA 90032-8201, USA.

出版信息

Carbohydr Res. 2014 May 22;390:42-5. doi: 10.1016/j.carres.2014.03.001. Epub 2014 Mar 13.

Abstract

The structure of the surface polysaccharide from a hypervirulent for mice Acinetobacter baumannii strain LAC-4 was studied. The polysaccharide was built of trisaccharide repeating units containing α-l-fucosamine, α-d-glucosamine, and α-8-epi-legionaminic acid. The structure interpretation was based mostly on NMR data. Polysaccharide was obtained using a procedure of LPS O-chain preparation, although whether it is an LPS O-chain or capsular polysaccharide remained unclear.

摘要

对一株对小鼠具有高毒力的鲍曼不动杆菌LAC-4菌株的表面多糖结构进行了研究。该多糖由含有α-L-岩藻糖胺、α-D-葡糖胺和α-8-表军团氨糖酸的三糖重复单元构成。结构解析主要基于核磁共振数据。多糖是采用脂多糖O抗原链制备方法获得的,不过它究竟是脂多糖O抗原链还是荚膜多糖仍不清楚。

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