Brown David, Weinberger Beth, Lewis Celia, Bonaparte Heather
Rev Environ Health. 2014;29(4):277-92. doi: 10.1515/reveh-2014-0002.
Case study descriptions of acute onset of respiratory, neurologic, dermal, vascular, abdominal, and gastrointestinal sequelae near natural gas facilities contrast with a subset of emissions research, which suggests that there is limited risk posed by unconventional natural gas development (UNGD). An inspection of the pathophysiological effects of acute toxic actions reveals that current environmental monitoring protocols are incompatible with the goal of protecting the health of those living and working near UNGD activities. The intensity, frequency, and duration of exposures to toxic materials in air and water determine the health risks to individuals within a population. Currently, human health risks near UNGD sites are derived from average population risks without adequate attention to the processes of toxicity to the body. The objective of this paper is to illustrate that current methods of collecting emissions data, as well as the analyses of these data, are not sufficient for accurately assessing risks to individuals or protecting the health of those near UNGD sites. Focusing on air pollution impacts, we examined data from public sources and from the published literature. We compared the methods commonly used to evaluate health safety near UNGD sites with the information that would be reasonably needed to determine plausible outcomes of actual exposures. Such outcomes must be based on the pathophysiological effects of the agents present and the susceptibility of residents near these sites. Our study has several findings. First, current protocols used for assessing compliance with ambient air standards do not adequately determine the intensity, frequency or durations of the actual human exposures to the mixtures of toxic materials released regularly at UNGD sites. Second, the typically used periodic 24-h average measures can underestimate actual exposures by an order of magnitude. Third, reference standards are set in a form that inaccurately determines health risk because they do not fully consider the potential synergistic combinations of toxic air emissions. Finally, air dispersion modeling shows that local weather conditions are strong determinates of individual exposures. Appropriate estimation of safety requires nested protocols that measure real time exposures. New protocols are needed to provide 1) continuous measures of a surrogate compound to show periods of extreme exposure; 2) a continuous screening model based on local weather conditions to warn of periodic high exposures; and 3) comprehensive detection of chemical mixtures using canisters or other devices that capture the major components of the mixtures.
天然气设施附近出现的呼吸道、神经、皮肤、血管、腹部和胃肠道后遗症急性发作的案例研究描述,与一部分排放研究形成对比,后者表明非常规天然气开发(UNGD)带来的风险有限。对急性毒性作用的病理生理效应进行检查后发现,当前的环境监测方案与保护在UNGD活动附近生活和工作的人们健康的目标不相容。空气和水中有毒物质的暴露强度、频率和持续时间决定了人群中个体的健康风险。目前,UNGD场地附近的人类健康风险是从平均人群风险得出的,而没有充分关注对身体的毒性过程。本文的目的是说明,当前收集排放数据的方法以及对这些数据的分析,不足以准确评估个体风险或保护UNGD场地附近人群的健康。以空气污染影响为重点,我们研究了来自公共来源和已发表文献的数据。我们将常用于评估UNGD场地附近健康安全的方法,与确定实际暴露可能结果合理所需的信息进行了比较。此类结果必须基于存在的物质的病理生理效应以及这些场地附近居民的易感性。我们的研究有几个发现。首先,用于评估是否符合环境空气质量标准的现行方案,不能充分确定实际人类接触UNGD场地定期释放的有毒物质混合物的强度、频率或持续时间。其次,通常采用的24小时定期平均测量可能会将实际暴露低估一个数量级。第三,参考标准的设定形式不准确地确定健康风险,因为它们没有充分考虑有毒空气排放的潜在协同组合。最后,空气扩散模型表明,当地天气状况是个体暴露的重要决定因素。适当的安全评估需要采用嵌套方案来测量实时暴露。需要新的方案来提供:1)对替代化合物的连续测量,以显示极端暴露时期;2)基于当地天气状况的连续筛查模型,以警告周期性高暴露;3)使用能捕获混合物主要成分的采样罐或其他设备对化学混合物进行全面检测。