肝移植：一项未完成的成果。
Liver transplantation: an unfinished product.
作者信息
Starzl T E, Todo S, Tzakis A G, Gordon R D, Makowka L, Stieber A, Podesta L, Yanaga K, Concepcion W, Iwatsuki S
机构信息
Department of Surgery, University of Pittsburgh Health Center, Pennsylvania.
出版信息
Transplant Proc. 1989 Feb;21(1 Pt 2):2197-200.
Abstract
Liver transplantation has become an extraordinarily valuable and useful operation, but one that is not perfect and that has not been exploited to anything like its full potential. Better immunosuppression may become available soon as exemplified by developments with the Japanese drug, FK506. Improved preservation with the UW solution is already here. With these advantages, liver transplantation is certain to become far more widely used than at any time in the past. Examples were cited of innovative approaches using liver transplantation for the treatment of hepatic malignancies.
摘要
肝移植已成为一项极具价值且实用的手术，但它并非完美无缺，其全部潜力也远未得到充分发挥。更好的免疫抑制方法可能很快就会出现，比如日本药物FK506的研发进展。UW溶液在肝脏保存方面的改进已经实现。有了这些优势，肝移植肯定会比过去任何时候都得到更广泛的应用。文中列举了一些创新性的方法，即利用肝移植治疗肝脏恶性肿瘤。
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本文引用的文献
1
Homotransplantation of multiple visceral organs.多个内脏器官的同种移植
Am J Surg. 1962 Feb;103:219-29. doi: 10.1016/0002-9610(62)90491-9.
2
Liver transplantation with use of cyclosporin a and prednisone.使用环孢素A和泼尼松进行肝移植。
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Evolution of liver transplantation.肝移植的发展历程。
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4
The use of heterologous antilymphoid agents in canine renal and liver homotransplantation and in human renal homotransplantation.异种抗淋巴细胞制剂在犬肾和肝同种移植以及人类肾同种移植中的应用。
Surg Gynecol Obstet. 1967 Feb;124(2):301-8.
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Experience in 1,000 liver transplants under cyclosporine-steroid therapy: a survival report.1000例接受环孢素-类固醇治疗的肝移植经验：一份生存报告。
Transplant Proc. 1988 Feb;20(1 Suppl 1):498-504.
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Effect of a new immunosuppressive agent, FK 506, on heterotopic cardiac allotransplantation in the rat.新型免疫抑制剂FK 506对大鼠异位心脏同种异体移植的影响。
Transplant Proc. 1987 Feb;19(1 Pt 2):1284-6.
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Immunosuppressive effect of FK-506 on in vitro lymphocyte alloactivation: synergism with cyclosporine A.FK-506对体外淋巴细胞同种异体激活的免疫抑制作用：与环孢素A的协同作用。
Transplant Proc. 1987 Oct;19(5 Suppl 6):40-4.
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