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[患者身体底物中痢疾抗原检测方法的比较诊断价值]

[Comparative diagnostic value of methods for detecting dysentery antigens in substrates of the patient's body].

作者信息

Li V H, Rubtsov I V, Tregub A V, Remneva T V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1989 Jan(1):57-61.

PMID:2469267
Abstract

The comparative evaluation of different immunological methods, such as the enzyme immunoassay, the aggregate hemagglutination test and the complement fixation test, used for the detection of specific Shigella antigens in biological body substrates obtained from 287 patients with acute dysentery caused by S. sonnei, S. flexneri and S. newcastle has been carried out. The enzyme immunoassay and the aggregate hemagglutination test most effective (97.5 +/- 0.5 and 92.4 +/- 0.9, respectively), the object of study being the patients' blood taken at the early stages of the disease. The diagnostic specificity of these methods has proved to be 98.7 +/- 6.7 and 95.2 +/- 1.4, respectively.

摘要

对287例由宋内志贺菌、福氏志贺菌和纽卡斯尔志贺菌引起的急性痢疾患者体内获取的生物基质中特定志贺菌抗原检测所使用的不同免疫学方法,如酶免疫测定法、凝集血细胞凝集试验和补体结合试验,进行了比较评估。酶免疫测定法和凝集血细胞凝集试验最为有效(分别为97.5±0.5和92.4±0.9),研究对象为疾病早期采集的患者血液。已证明这些方法的诊断特异性分别为98.7±6.7和95.2±1.4。

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