Methodist Health System of Dallas, Dallas, TX, USA.
Physician Senior Services, Dallas, TX, USA.
Am Fam Physician. 2014 Apr 1;89(7):569-73.
Intertrigo is a superficial inflammatory dermatitis occurring on two closely opposed skin surfaces as a result of moisture, friction, and lack of ventilation. Bodily secretions, including perspiration, urine, and feces, often exacerbate skin inflammation. Physical examination of skin folds reveals regions of erythema with peripheral scaling. Excessive friction and inflammation can cause skin breakdown and create an entry point for secondary fungal and bacterial infections, such as Candida, group A beta-hemolytic streptococcus, and Corynebacterium minutissimum. Candidal intertrigo is commonly diagnosed clinically, based on the characteristic appearance of satellite lesions. Diagnosis may be confirmed using a potassium hydroxide preparation. Resistant cases require oral fluconazole therapy. Bacterial superinfections may be identified with bacterial culture or Wood lamp examination. Fungal lesions are treated with topical nystatin, clotrimazole, ketoconazole, oxiconazole, or econazole. Secondary streptococcal infections are treated with topical mupirocin or oral penicillin. Corynebacterium infections are treated with oral erythromycin.
间擦疹是一种发生于两个紧密相邻皮肤表面的浅表炎症性皮肤病，是由于潮湿、摩擦和通风不良引起的。体液分泌物，包括汗液、尿液和粪便，常使皮肤炎症恶化。对皮肤褶皱进行体格检查，可发现红斑区域，周边有鳞屑。过度摩擦和炎症会导致皮肤破裂，并为继发真菌感染和细菌感染（如白色念珠菌、A 组β溶血性链球菌和微小棒状杆菌）创造入口。基于卫星病变的特征性表现，临床上通常可诊断为念珠菌性间擦疹。可通过氢氧化钾制剂来确认诊断。耐药病例需要口服氟康唑治疗。细菌感染可通过细菌培养或伍德灯检查来识别。真菌病变用局部制霉菌素、克霉唑、酮康唑、奥昔康唑或益康唑治疗。继发链球菌感染用局部莫匹罗星或口服青霉素治疗。棒状杆菌感染用口服红霉素治疗。
