Mashru Mayur, Galib R, Shukla Vinay J, Ravishankar B, Prajapati Pradeep Kumar
Superintendent, Government Ayurved Hospital Popatpura, Godhra, India.
Assistant Professor, Department of Rasashastra and Bhaishajya Kalpana, Institute for Post Graduate Teaching and Research in Ayurveda, Jamnagar, Gujarat, India.
Ayu. 2013 Oct;34(4):346-51. doi: 10.4103/0974-8520.127692.
Asthma represents a profound world-wide public health problem. The most effective anti-asthmatic drugs currently available include β2-agonists and glucocorticoids which can controls asthma in about 90-95% of patients. In Ayurveda, this miserable condition is comparable with Tamaka Shwasa type of Shwasa Roga. In the present study, 52 patients were treated with Sameera Pannaga Rasa at a dose of 30 mg twice a day for 4 weeks along with Nagavallidala (leaf of Piper betel Linn.) The results were assessed in terms of clinical recovery, symptomatic relief, pulmonary function improvement and on subjective and objective parameters. A significant improvement in subjective parameters, control on asthma, recurrence of asthma, increase in peak expiratory flow rate, considerable decrease in total and absolute, acute eosinophil count and erythrocyte sedimentation rate were observed. Overall marked improvement was found in 33.33%, moderate improvement in 44.44% and mild improvement in 20.00% was observed. The study reveals that Sameera Pannaga Rasa can be used as an effective drug in bronchial asthma.
哮喘是一个严重的全球性公共卫生问题。目前可用的最有效的抗哮喘药物包括β2受体激动剂和糖皮质激素，它们可控制约90 - 95%患者的哮喘症状。在阿育吠陀医学中，这种痛苦的病症与塔玛卡·什瓦萨（Tamaka Shwasa）类型的什瓦萨病（Shwasa Roga）相当。在本研究中，52例患者接受了萨梅拉·潘纳加·拉萨（Sameera Pannaga Rasa）治疗，剂量为每日两次，每次30毫克，持续4周，同时服用那加瓦利达拉（Nagavallidala，即蒌叶）。根据临床康复、症状缓解、肺功能改善以及主观和客观参数对结果进行评估。观察到主观参数有显著改善、哮喘得到控制、哮喘复发率降低、呼气峰值流速增加、总嗜酸性粒细胞计数和绝对嗜酸性粒细胞计数以及红细胞沉降率大幅下降。总体而言，33.33%的患者有显著改善，44.44%的患者有中度改善，20.00%的患者有轻度改善。该研究表明，萨梅拉·潘纳加·拉萨可作为治疗支气管哮喘的有效药物。
