Tseng Pao-Yu, Lai Yu-Shih, Chen Mu-Kuan, Shen Ko-Hung
Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital Changhua, Taiwan.
Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital Changhua, Taiwan ; Institute of Medicine, Chung Shan Medical University Taichung, Taiwan.
Int J Clin Exp Pathol. 2014 Feb 15;7(3):1224-8. eCollection 2014.
Leiomyomas are benign myogenic tumors that seldom occur in the sinonasal cavity. They were commonly found in middle-aged adults with a female predominance. Clinical symptoms include nasal obstruction with discharge, nasal bleeding and pain. We describe the case of a 48 year-old woman with a leiomyoma arising from right inferior nasal turbinate. Transnasal endoscopic excision was performed with satisfied result. The tumor was found to be progesterone receptor positive on immunohistochemical analysis. The clinical findings are addressed with a review of the literature. To the best of our knowledge, this is the third reported case that supports the growth of the tumor may be hormone-dependent.
平滑肌瘤是一种良性肌源性肿瘤，很少发生于鼻腔鼻窦。其常见于中年成年人，女性居多。临床症状包括鼻塞伴流涕、鼻出血和疼痛。我们报道一例48岁女性，其平滑肌瘤起源于右下鼻甲。经鼻内镜切除术后效果满意。免疫组化分析发现肿瘤孕激素受体呈阳性。本文结合文献复习对临床发现进行了探讨。据我们所知，这是第三例支持肿瘤生长可能依赖激素的报道病例。
