Vaidya Anuradha, Singhania Smita
Symbiosis School of Biomedical Sciences (SSBS), Symbiosis International University (SIU), Gram: Lavale, Taluka: Mulshi, Pune, Maharashtra, India
J Stem Cells. 2013;8(2):105-13.
Umbilical cord blood (UCB) is a potential source of primitive hematopoietic stem and progenitor cells (HSPC) available for clinical application to reconstitute the hematopoietic system in patients lacking conventional stem cell donors. In the last decade because the frequency of UCB stem cell transplantation has increased, the quality of UCB available in banks has become an important criterion for the success of any UCB stem cell transplant. Moreover, with the growing numbers of cord blood banks there is not only a need to improvise quality issues but to also develop a more homogenous approach in setting standards and regulations for assessing them. The present article provides an insight on the importance of cord blood banking in India and the impending requirement to provide clarity on certain issues regarding UCB banking. Furthermore, the article discusses about certain practical approaches which could perhaps be referred to as guidelines (and by no means be solely adopted as the only measures) by cord blood banks in India for establishing or maintaining a standard for quality control (QC) measures.
脐带血（UCB）是原始造血干细胞和祖细胞（HSPC）的潜在来源，可用于临床应用，为缺乏传统干细胞供体的患者重建造血系统。在过去十年中，由于脐带血干细胞移植的频率增加，血库中可用的脐带血质量已成为任何脐带血干细胞移植成功的重要标准。此外，随着脐带血库数量的不断增加，不仅需要改进质量问题，还需要制定更统一的方法来设定评估它们的标准和法规。本文深入探讨了印度脐带血库的重要性以及明确脐带血库某些问题的迫切需求。此外，本文还讨论了一些实用方法，印度脐带血库或许可将其作为建立或维持质量控制（QC）措施标准的指导方针（绝不能仅将其作为唯一措施）。
