Man in 't Veld A J, van den Meiracker A H, Schalekamp M A
Department of Internal Medicine I, University Hospital Dijkzigt, Erasmus University Rotterdam, The Netherlands.
J Cardiovasc Pharmacol. 1988;12 Suppl 8:S93-9.
Patient selection, trial design, methodology of blood pressure measurement, experimental conditions, and methods of statistical analysis may be all determinants of real or spurious relationships in clinical hypertension research. Our study of 52 hypertensive subjects, in which we analyzed acute and long-term treatment responses, does not demonstrate an age dependency of blood pressure response to treatment with beta-adrenoceptor antagonists.
患者选择、试验设计、血压测量方法、实验条件以及统计分析方法可能都是临床高血压研究中真实或虚假关系的决定因素。我们对52名高血压患者进行了研究，分析了急性和长期治疗反应，结果并未显示血压对β-肾上腺素能受体拮抗剂治疗的反应存在年龄依赖性。
