针刺和感觉神经肽可增加大鼠皮肤血流量。

Acupuncture and sensory neuropeptides increase cutaneous blood flow in rats.

作者信息

Jansen G, Lundeberg T, Kjartansson J, Samuelson U E

机构信息

Department of Physiology, Karolinska Institute, Stockholm, Sweden.

出版信息

Neurosci Lett. 1989 Feb 27;97(3):305-9. doi: 10.1016/0304-3940(89)90615-0.

DOI:10.1016/0304-3940(89)90615-0

PMID:2469996

Abstract

The effect on blood flow of electro-acupuncture (EA) injection of substance P (SP) and calcitonin gene-related peptide (CGRP) was studied in musculocutaneous flaps in the rat, using laser Doppler flowmetry. The circulatory border was estimated before and after treatment. It was shown that treatment with EA increased the blood flow moving the circulatory border distally 66% after a treatment. Injection of NaCl into the dorsal central vein of the flap resulted in no increase in blood flow whereas SP 10(-9) M and CGRP 10(-9) M increased the blood flow so that the circulatory border moved distally 31% and 49%, respectively. It is suggested that the effect of EA on blood flow is similar to the effect achieved by injecting CGRP and SP.

摘要

采用激光多普勒血流仪，研究了电针（EA）注射P物质（SP）和降钙素基因相关肽（CGRP）对大鼠肌皮瓣血流的影响。在治疗前后评估循环边界。结果表明，电针治疗可增加血流量，治疗后循环边界向远端移动66%。向皮瓣背侧中央静脉注射氯化钠不会增加血流量，而注射10^(-9)M的SP和10^(-9)M的CGRP可增加血流量，使循环边界分别向远端移动31%和49%。提示电针影响血流的作用与注射CGRP和SP的作用相似。