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降钙素基因相关肽(CGRP)和经皮电神经刺激(TENS)可增加大鼠肌皮瓣的皮肤血流量。

Calcitonin gene-related peptide (CGRP) and transcutaneous electrical nerve stimulation (TENS) increase cutaneous blood flow in a musculocutaneous flap in the rat.

作者信息

Kjartansson J, Lundeberg T, Samuelson U E, Dalsgaard C J, Hedén P

机构信息

Department of Plastic and Reconstructive Surgery, Karolinska Hospital, Stockholm, Sweden.

出版信息

Acta Physiol Scand. 1988 Sep;134(1):89-94. doi: 10.1111/j.1748-1716.1988.tb08463.x.

DOI:10.1111/j.1748-1716.1988.tb08463.x
PMID:3266418
Abstract

The effect of blood flow on transcutaneous electrical nerve stimulation (TENS) and injection of calcitonin gene-related peptide (CGRP) was studied in a musculocutaneous flap of the rat, using laser Doppler flowmetry. The circulatory border was estimated before and after treatment. It was shown that repeated treatments with TENS gradually increased the blood flow, moving the circulatory border distally more than 100% after three treatments. Injection of NaCl into the dorsal central vein of the flap resulted in no increase in blood flow, whereas CGRP 10(-10) M increased the blood flow, so that the circulatory border moved distally 70% and 60%, respectively.

摘要

采用激光多普勒血流仪,在大鼠的肌皮瓣中研究了血流对经皮电刺激神经疗法(TENS)和降钙素基因相关肽(CGRP)注射的影响。在治疗前后评估循环边界。结果表明,重复进行TENS治疗可逐渐增加血流量,三次治疗后循环边界向远端移动超过100%。向皮瓣背侧中央静脉注射氯化钠不会导致血流量增加,而注射10(-10) M的CGRP可使血流量增加,循环边界分别向远端移动70%和60%。

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Calcitonin gene-related peptide (CGRP) and transcutaneous electrical nerve stimulation (TENS) increase cutaneous blood flow in a musculocutaneous flap in the rat.降钙素基因相关肽(CGRP)和经皮电神经刺激(TENS)可增加大鼠肌皮瓣的皮肤血流量。
Acta Physiol Scand. 1988 Sep;134(1):89-94. doi: 10.1111/j.1748-1716.1988.tb08463.x.
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