Fiume D, Palombi M, Sciassa V, Tamorri M
Neurosurgery Division, S. Filippo Neri Hospital, Rome, Italy.
Pacing Clin Electrophysiol. 1989 Apr;12(4 Pt 2):698-704. doi: 10.1111/j.1540-8159.1989.tb02718.x.
Between 1982 and 1987, 45 patients suffering from painful symptomatology caused by peripheral vascular disease, not curable by medical or surgical therapy, were implanted with epidural neurological stimulators. Measurements used in evaluating the effectiveness of the method were pain control, walking distance, and development of trophic problems. With most patients, we noted a satisfactory and long-lasting degree of pain control. Walking distance increased to a surprising degree. Trophic lesions smaller than 3 sq cm healed, while lesions of greater size required amputation of the limb. Transcutaneous oxygen tension (TcpO2) was used to study the effects of SCS on peripheral circulation in implanted patients. In addition, TcpO2 was calculated in 15 patients before and during the percutaneous test to predict the effectiveness of SCS. Regression of painful symptomatology was achieved only in patients whose TcpO2 improved during the course of the testing. Therefore, this method provides an objective measure for the implantation of neurostimulator.
1982年至1987年间，45名因周围血管疾病导致疼痛症状且无法通过药物或手术治疗治愈的患者接受了硬膜外神经刺激器植入。评估该方法有效性的指标包括疼痛控制、步行距离以及营养问题的发展情况。对于大多数患者，我们注意到疼痛控制程度令人满意且持久。步行距离有了惊人的增加。面积小于3平方厘米的营养性病变愈合，而较大面积的病变则需要截肢。经皮氧分压（TcpO2）用于研究脊髓电刺激（SCS）对植入患者外周循环的影响。此外，在15名患者的经皮测试前后计算TcpO2，以预测SCS的有效性。只有在测试过程中TcpO2有所改善的患者才实现了疼痛症状的消退。因此，该方法为神经刺激器的植入提供了一种客观的测量方法。
