Naik Shweta, Sharma Jyoti, Yengkom Rameshwor, Kalrao Vijay, Mulay Atul
Department of Pediatrics, BVDUMC, Consultant Nephrologist, Viva Kidney Suraksha, Pune, Maharashtra, India.
Department of Pediatrics, MD Medicine, Consultant Nephrologist, Viva Kidney Suraksha, Pune, Maharashtra, India.
Indian J Crit Care Med. 2014 Mar;18(3):129-33. doi: 10.4103/0972-5229.128701.
Acute kidney injury (AKI) is common in patients in the pediatric intensive care unit (PICU) and is associated with poor outcome. We conducted the present study to determine the incidence, risk factors and outcomes of AKI in the PICU.
We collected data retrospectively from case records of children admitted to the PICU during one year. We defined and classified AKI according to modified pRIFLE criteria. We used multivariate logistic regression to determine risk factors of AKI and association of AKI with mortality and morbidity.
Of the 252 children included in the study, 103 (40.9%) children developed AKI. Of these 103 patients with AKI, 39 (37.9%) patients reached pRIFLE max of Risk, 37 (35.9%) patients reached Injury, and 27 (26.2%) had Failure. Mean Pediatric Risk of Mortality (PRISM III) score at admission was higher in patients with AKI than in controls (P < 0.001).
急性肾损伤（AKI）在儿科重症监护病房（PICU）患者中很常见，且与不良预后相关。我们开展本研究以确定PICU中AKI的发病率、危险因素及预后情况。
我们回顾性收集了一年内入住PICU的儿童病例记录中的数据。我们根据改良的pRIFLE标准对AKI进行定义和分类。我们使用多因素逻辑回归来确定AKI的危险因素以及AKI与死亡率和发病率的关联。
在纳入研究的252名儿童中，103名（40.9%）儿童发生了AKI。在这103例AKI患者中，39例（37.9%）患者达到了pRIFLE分级中的“风险”最高级别，37例（35.9%）患者达到“损伤”级别，27例（26.2%）患者达到“衰竭”级别。AKI患者入院时的平均儿科死亡风险（PRISM III）评分高于对照组（P < 0.001）。
