Spiridonova V A, Akhmanova A S, Kagramanova V K, Köpke A K, Mankin A S
Belozersky Laboratory of Molecular Biology and Bioorganic Chemistry, Moscow State University, USSR.
Can J Microbiol. 1989 Jan;35(1):153-9. doi: 10.1139/m89-023.
A 1643 base pair fragment encoding the S3 and L29 equivalent ribosomal proteins has been sequenced from the archaebacterium Halobacterium halobium. The incomplete open reading frame present upstream from the S3 gene encodes a protein homologous to the eubacterial ribosomal protein L22. The initiation codons of the S3 and L29 genes overlap with the termination codons of the upstream genes. A tight physical organization suggests that these genes are transcribed as a polycistronic operon. Peculiarities of the protein structure and gene organization are discussed.
已对来自嗜盐古菌盐生盐杆菌的一段编码S3和L29等效核糖体蛋白的1643个碱基对片段进行了测序。S3基因上游存在的不完整开放阅读框编码一种与真细菌核糖体蛋白L22同源的蛋白质。S3和L29基因的起始密码子与上游基因的终止密码子重叠。紧密的物理组织表明这些基因作为多顺反子操纵子进行转录。文中讨论了蛋白质结构和基因组织的特点。