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Chemerin, a novel player in inflammatory bowel disease.

作者信息

Buechler C

出版信息

Cell Mol Immunol. 2014 Jul;11(4):315-6. doi: 10.1038/cmi.2014.14. Epub 2014 Apr 7.

DOI:10.1038/cmi.2014.14
PMID:24705196
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4085516/
Abstract
摘要

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2
Chemerin aggravates DSS-induced colitis by suppressing M2 macrophage polarization.凯莫瑞因通过抑制M2巨噬细胞极化加重右旋糖酐硫酸钠诱导的结肠炎。
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Chemerin reveals its chimeric nature.凯莫瑞蛋白展现出其嵌合性质。
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Impact of Obesity on the Course of Management of Inflammatory Bowel Disease-A Review.肥胖对炎症性肠病管理过程的影响——综述。
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Adipokines: New Potential Therapeutic Target for Obesity and Metabolic, Rheumatic, and Cardiovascular Diseases.脂肪因子:肥胖及代谢性、风湿性和心血管疾病的新潜在治疗靶点。
Front Physiol. 2020 Oct 30;11:578966. doi: 10.3389/fphys.2020.578966. eCollection 2020.
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Chemerin Isoforms and Activity in Obesity.肥胖症中趋化素同工型及其活性。
Int J Mol Sci. 2019 Mar 5;20(5):1128. doi: 10.3390/ijms20051128.
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Serum chemerin levels are independently associated with quality of life in colorectal cancer survivors: A pilot study.血清凯莫瑞水平与结直肠癌幸存者的生活质量独立相关:一项试点研究。
PLoS One. 2017 May 5;12(5):e0176929. doi: 10.1371/journal.pone.0176929. eCollection 2017.
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Evaluation of chemerin and its receptors, ChemR23 and CCRL2, in gingival tissues with healthy and periodontitis.在健康和牙周炎牙龈组织中对chemerin及其受体ChemR23和CCRL2的评估。
Odontology. 2018 Jan;106(1):29-36. doi: 10.1007/s10266-017-0297-2. Epub 2017 Feb 23.
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Adipokines and the role of visceral adipose tissue in inflammatory bowel disease.脂肪因子及内脏脂肪组织在炎症性肠病中的作用
Ann Gastroenterol. 2016 Oct-Dec;29(4):424-438. doi: 10.20524/aog.2016.0077. Epub 2016 Sep 6.

本文引用的文献

1
Chemerin aggravates DSS-induced colitis by suppressing M2 macrophage polarization.凯莫瑞因通过抑制M2巨噬细胞极化加重右旋糖酐硫酸钠诱导的结肠炎。
Cell Mol Immunol. 2014 Jul;11(4):355-66. doi: 10.1038/cmi.2014.15. Epub 2014 Apr 14.
2
Chemerin is highly expressed in hepatocytes and is induced in non-alcoholic steatohepatitis liver.Chemerin 在肝细胞中高度表达,并在非酒精性脂肪性肝炎肝中被诱导。
Exp Mol Pathol. 2013 Oct;95(2):199-205. doi: 10.1016/j.yexmp.2013.07.009. Epub 2013 Jul 29.
3
The chemerin/ChemR23 system does not affect the pro-inflammatory response of mouse and human macrophages ex vivo.Chemerin/ChemR23 系统不会影响体外培养的小鼠和人巨噬细胞的促炎反应。
PLoS One. 2012;7(6):e40043. doi: 10.1371/journal.pone.0040043. Epub 2012 Jun 29.
4
"Metabolic aspects" in inflammatory bowel diseases.炎症性肠病的代谢方面。
Curr Drug Deliv. 2012 Jul;9(4):326-32. doi: 10.2174/156720112801323044.
5
Intestinal macrophages - specialised adaptation to a unique environment.肠道巨噬细胞——对独特环境的专门适应。
Eur J Immunol. 2011 Sep;41(9):2494-8. doi: 10.1002/eji.201141714.
6
Chemerin: at the crossroads of inflammation and obesity.趋化素:炎症与肥胖的交汇点。
Trends Endocrinol Metab. 2010 Nov;21(11):660-7. doi: 10.1016/j.tem.2010.08.001.
7
Circulating levels of chemerin and adiponectin are higher in ulcerative colitis and chemerin is elevated in Crohn's disease.循环中 chemerin 和脂联素的水平在溃疡性结肠炎中较高,而 chemerin 在克罗恩病中升高。
Inflamm Bowel Dis. 2010 Apr;16(4):630-7. doi: 10.1002/ibd.21091.
8
Resolvin E1, an endogenous lipid mediator derived from eicosapentaenoic acid, prevents dextran sulfate sodium-induced colitis.内源性脂类介质 resolvin E1 来源于二十碳五烯酸,可预防葡聚糖硫酸钠诱导的结肠炎。
Inflamm Bowel Dis. 2010 Jan;16(1):87-95. doi: 10.1002/ibd.21029.
9
Epithelial cells in fetal intestine produce chemerin to recruit macrophages.胎儿肠道中的上皮细胞产生趋化素以招募巨噬细胞。
Am J Physiol Gastrointest Liver Physiol. 2009 Jul;297(1):G1-G10. doi: 10.1152/ajpgi.90730.2008. Epub 2009 May 14.
10
The genetics and immunopathogenesis of inflammatory bowel disease.炎症性肠病的遗传学与免疫发病机制
Nat Rev Immunol. 2008 Jun;8(6):458-66. doi: 10.1038/nri2340.