Lagrèze W, Metzger M, Rössler J
Klinik für Augenheilkunde, Universitätsklinikum Freiburg, 79106, Freiburg, Deutschland,
Ophthalmologe. 2014 May;111(5):479-81. doi: 10.1007/s00347-014-3046-8.
Orbital lymphangiomas are mostly congenital, apparent vascular space-occupying lesions, which can lead to disfiguring swelling of the periorbital soft tissues, ocular motility disorders, optic nerve compression and keratopathy. The treatment is challenging because the disease is principally incurable. Lymphangiomatous tissue can be surgically partially reduced or treated by intralesional injection of various sclerosants. In this review we report the successful use of OK-432 for destruction of a macrocystic orbital lymphangioma.
眼眶淋巴管瘤大多为先天性,是明显的血管占位性病变,可导致眶周软组织毁容性肿胀、眼球运动障碍、视神经受压及角膜病变。由于该疾病基本上无法治愈,其治疗具有挑战性。淋巴管瘤组织可通过手术部分切除或瘤内注射各种硬化剂进行治疗。在本综述中,我们报告了OK-432成功用于破坏巨大囊性眼眶淋巴管瘤的情况。