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眼眶淋巴管瘤:治疗策略综述。

Orbital lymphangiomas: a review of management strategies.

机构信息

Oculoplastic and Craniofacial Service, Chelsea and Westminster Hospital, London, UK.

出版信息

Curr Opin Ophthalmol. 2012 Sep;23(5):433-8. doi: 10.1097/ICU.0b013e3283560a99.

DOI:10.1097/ICU.0b013e3283560a99
PMID:22828166
Abstract

PURPOSE OF REVIEW

Orbital lymphangiomas present a difficult management problem for the ophthalmologist. This review offers a strategy for managing the condition.

RECENT FINDINGS

There have been recent publications discussing the use of intralesional fibrin glue to aid dissection and intralesional sclerosant to shrink the lesion. We discuss the evidence for these treatments and present a case in which these treatments were combined.

SUMMARY

This review highlights the classification and presents management options for orbital lymphangioma. We encourage a holistic and individualized approach to the patients, recognizing the variety of clinical manifestations that the condition can cause. In the event of surgical excision, we present the evidence for the use of intralesional fibrin glue and intralesional sclerosant, and describe using both in the same case.

摘要

目的综述

眼眶淋巴管瘤的治疗对眼科医生来说是一个具有挑战性的问题。本文提供了一种处理这种疾病的策略。

最近的发现

最近有一些出版物讨论了使用腔内纤维蛋白胶辅助解剖和腔内硬化剂缩小病变。我们讨论了这些治疗方法的证据,并介绍了一个联合使用这些治疗方法的病例。

总结

本文重点介绍了眼眶淋巴管瘤的分类,并提出了治疗选择。我们鼓励对患者进行全面和个性化的治疗,认识到该疾病可能导致的各种临床表现。在进行手术切除的情况下,我们提供了使用腔内纤维蛋白胶和腔内硬化剂的证据,并描述了在同一病例中同时使用这两种药物的情况。

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1
Orbital lymphangiomas: a review of management strategies.眼眶淋巴管瘤:治疗策略综述。
Curr Opin Ophthalmol. 2012 Sep;23(5):433-8. doi: 10.1097/ICU.0b013e3283560a99.
2
Sclerosing therapy as first line treatment for low flow vascular lesions of the orbit.硬化治疗作为眼眶低流量血管病变的一线治疗方法。
Am J Ophthalmol. 2006 Feb;141(2):333-9. doi: 10.1016/j.ajo.2005.09.026.
3
Subtotal excision with adjunctive sclerosing therapy for the treatment of severe symptomatic orbital lymphangiomas.采用辅助硬化治疗的次全切除术治疗严重症状性眼眶淋巴管瘤。
Arch Ophthalmol. 2011 Aug;129(8):1073-6. doi: 10.1001/archophthalmol.2011.204.
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Sotradecol (sodium tetradecyl sulfate) injection of orbital lymphangioma.十四烷基硫酸钠注射治疗眼眶淋巴管瘤。
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Intralesional injection of Tisseel fibrin glue for resection of lymphangiomas and other thin-walled orbital cysts.瘤内注射Tisseel纤维蛋白胶用于淋巴管瘤及其他薄壁眼眶囊肿的切除。
Ophthalmic Plast Reconstr Surg. 2005 May;21(3):171-6. doi: 10.1097/01.iop.0000160594.06829.00.
6
[Sclerotization of orbital lymphangioma with OK-432].[用OK-432硬化眼眶淋巴管瘤]
Ophthalmologe. 2014 May;111(5):479-81. doi: 10.1007/s00347-014-3046-8.
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Update on orbital lymphatic malformations.眼眶淋巴管畸形的最新进展。
Curr Opin Ophthalmol. 2016 Sep;27(5):413-5. doi: 10.1097/ICU.0000000000000291.
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Successful treatment of orbital lymphangioma with intralesional bleomycin and application of continuous negative pressure.采用瘤内注射博来霉素及持续负压吸引成功治疗眼眶淋巴管瘤。
Korean J Ophthalmol. 2015 Feb;29(1):70-2. doi: 10.3341/kjo.2015.29.1.70.
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[A variety of orbital lymphangioma treatments: one case treated with orbital decompression therapy and the other case with intralesional injection of OK-432 therapy].[多种眼眶淋巴管瘤治疗方法:1例采用眼眶减压治疗,另1例采用瘤内注射OK-432治疗]
Nippon Ganka Gakkai Zasshi. 2009 Jul;113(7):732-40.
10
Sclerotherapy for Orbital Lymphangioma - Case Series and Literature Review.眼眶淋巴管瘤的硬化治疗——病例系列与文献综述
In Vivo. 2017 Mar-Apr;31(2):263-266. doi: 10.21873/invivo.11055.

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Role of intralesional bleomycin sclerotherapy as the sole or adjunct treatment of superficial ocular adnexal lymphatic malformations.腔内博来霉素硬化治疗作为眼附属器浅表淋巴管畸形的单一或辅助治疗手段的作用。
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