Patel Karnesh Chandrakant, Kalantzis George, El-Hindy Nabil, Chang Bernard Y
Department of Ophthalmology, Huddersfield Royal Infirmary, Huddersfield, U.K.
Department of Ophthalmology, St. James' University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, U.K.
In Vivo. 2017 Mar-Apr;31(2):263-266. doi: 10.21873/invivo.11055.
Orbital lymphangioma is a lymphatic system lesion that commonly presents in childhood. Management of these lesions is complex. Sclerotherapy is a therapy used to treat and shrink lesions prior to or as an alternative to surgery. We present three cases of orbital lymphangioma that were treated with sclerotherapy. Case 1: A 6-month-old boy was presented in 2010 with right ptosis and proptosis. Magnetic resonance imaging (MRI) identified a lesion involving the right orbit and face. Case 2: A 3-year-old girl was presented in 2011 with intermittent right periorbital swelling and medial canthal bleeding. MRI identified a soft-tissue lesion in the right orbit, extending into the face. Case 3: A 3-year-old girl was presented in 2012 with vomiting, and painful right proptosis. MRI identified an intra-conal lesion in the right orbit with fluid filled levels. All three patients were treated with sclerotherapy (sodium tetradecylsulfate). Sclerotherapy is a promising treatment for orbital lymphangioma. Its use may prevent the need for, or minimise the amount of surgical management. Several sclerosants are now commonly used to treat these lesions.
眼眶淋巴管瘤是一种常见于儿童期的淋巴系统病变。这些病变的治疗很复杂。硬化疗法是一种在手术前用于治疗和缩小病变或作为手术替代方法的治疗手段。我们报告三例接受硬化疗法治疗的眼眶淋巴管瘤病例。病例1：一名6个月大的男婴于2010年出现右眼睑下垂和眼球突出。磁共振成像（MRI）检查发现一个累及右眼眶和面部的病变。病例2：一名3岁女童于2011年出现间歇性右眶周肿胀和内眦出血。MRI检查发现右眼眶有一个软组织病变，延伸至面部。病例3：一名3岁女童于2012年出现呕吐及右侧眼球突出伴疼痛。MRI检查发现右眼眶锥内病变，有液平面。所有三名患者均接受了硬化疗法（十四烷基硫酸钠）治疗。硬化疗法是治疗眼眶淋巴管瘤的一种有前景的治疗方法。其应用可能避免手术治疗的需要或减少手术治疗的范围。目前有几种硬化剂常用于治疗这些病变。
