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后部可逆性脑病的非典型表现:见于一名患有双侧IV级膀胱输尿管反流的儿童。

Atypical presentation of posterior reversible encephalopathy: in a child with bilateral grade IV vesicoureteric reflux.

作者信息

Sharma Shobha, Gupta Ratan, Sehgal Rachna, Aggarwal Kailash Chandra

机构信息

Department of Pediatrics, VMMC & Safdarjung Hospital, New Delhi, India.

Department of Pediatrics, VMMC & Safdarjung Hospital, New Delhi, India

出版信息

J Trop Pediatr. 2014 Aug;60(4):331-3. doi: 10.1093/tropej/fmu019. Epub 2014 Apr 3.

Abstract

Posterior reversible encephalopathy, better known as potential reversible encephalopathy syndrome (PRES), is a clinicoradiological entity mostly described in adult populations manifesting predominantly as bilateral symmetrical diffuse white matter vasogenic oedema in parieto-occipital regions. Rarely it may also present as patchy reversible areas of involvement in the basal ganglia, brainstem and deep white matter. It is reported scarcely in childhood populations. Frequent association with acute hypertension (67-80%) is reported in many studies. Involvement of the brainstem and cervical cord (apart from the typical parieto-occipital lesions) is an extremely rare imaging manifestation of PRES and its recognition is important to avoid misdiagnosis as myelitis or acute disseminated encephalomyelitis by proper clinical correlation. We hereby report a case of PRES in a 7-year-old child showing an uncommon pattern on imaging study involving the brain as well as the brainstem and cervical spinal cord.

摘要

后部可逆性脑病,更确切地称为潜在可逆性脑病综合征(PRES),是一种临床放射学实体,主要在成人中描述,主要表现为双侧对称的顶枕叶区域弥漫性白质血管源性水肿。很少情况下,它也可能表现为基底节、脑干和深部白质的斑片状可逆性受累区域。在儿童人群中鲜有报道。许多研究报告其常与急性高血压相关(67-80%)。脑干和颈髓受累(除典型的顶枕叶病变外)是PRES极为罕见的影像学表现,通过适当的临床关联来识别这一点对于避免误诊为脊髓炎或急性播散性脑脊髓炎很重要。我们在此报告一例7岁儿童的PRES病例,其影像学研究显示出一种不常见的模式,累及大脑以及脑干和颈髓。

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