Kollef Marin H, Chen Yixin, Heard Kevin, LaRossa Gina N, Lu Chenyang, Martin Nathan R, Martin Nelda, Micek Scott T, Bailey Thomas
Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, Missouri.
J Hosp Med. 2014 Jul;9(7):424-9. doi: 10.1002/jhm.2193. Epub 2014 Apr 7.
Episodes of patient deterioration on hospital units are expected to increasingly contribute to morbidity and healthcare costs.
To determine if real-time alerts sent to the rapid response team (RRT) improved patient care.
Randomized, controlled trial.
Eight medicine units (Barnes-Jewish Hospital).
Five hundred seventy-one patients.
Real-time alerts generated by a validated deterioration algorithm were sent real-time to the RRT (intervention) or hidden (control).
Intensive care unit (ICU) transfer, hospital mortality, hospital duration.
ICU transfer (17.8% vs 18.2%; odds ratio: 0.972; 95% confidence interval [CI]: 0.635-1.490) and hospital mortality (7.3% vs 7.7%; odds ratio: 0.947; 95% CI: 0.509-1.764) were similar for the intervention and control groups. The number of patients requiring transfer to a nursing home or long-term acute care hospital was similar for patients in the intervention and control groups (26.9% vs 26.3%; odds ratio: 1.032; 95% CI: 0.712-1.495). Hospital duration (8.4 ± 9.5 days vs 9.4 ± 11.1 days; P = 0.038) was statistically shorter for the intervention group. The number of RRT calls initiated by the primary care team was similar for the intervention and control groups (19.9% vs 16.5%; odds ratio: 1.260; 95% CI: 0.823-1.931).
Real-time alerts sent to the RRT did not reduce ICU transfers, hospital mortality, or the need for subsequent long term care. However, hospital length of stay was modestly reduced.
医院病房内患者病情恶化的情况预计将越来越多地导致发病率上升和医疗成本增加。
确定发送给快速反应团队(RRT)的实时警报是否能改善患者护理。
随机对照试验。
八个内科病房(巴恩斯-犹太医院)。
571名患者。
由经过验证的病情恶化算法生成的实时警报被实时发送给RRT(干预组)或隐藏起来(对照组)。
重症监护病房(ICU)转诊、医院死亡率、住院时间。
干预组和对照组的ICU转诊率(17.8%对18.2%;比值比:0.972;95%置信区间[CI]:0.635 - 1.490)和医院死亡率(7.3%对7.7%;比值比:0.947;95% CI:0.509 - 1.764)相似。干预组和对照组中需要转至疗养院或长期急性护理医院的患者数量相似(26.9%对26.3%;比值比:1.032;95% CI:0.712 - 1.495)。干预组的住院时间(8.4 ± 9.5天对9.4 ± 11.1天;P = 0.038)在统计学上更短。初级护理团队发起的RRT呼叫次数在干预组和对照组中相似(19.9%对16.5%;比值比:1.260;95% CI:0.823 - 1.931)。
发送给RRT的实时警报并未降低ICU转诊率、医院死亡率或后续长期护理的需求。然而,住院时间略有缩短。