Brown A C, Stevenson L M, Leonard H M, Nieves-Puigdoller K, Clotfelter E D
Department of Biology, Amherst College, Amherst, MA 01002, USA ; Graduate Program in Organismic and Evolutionary Biology, University of Massachusetts, Amherst, MA 01003, USA ; Department of Embryology, Carnegie Institute of Washington, Baltimore, MD 21218, USA.
Department of Biology, Amherst College, Amherst, MA 01002, USA ; Doctoral Program in Ecology, Evolution and Marine Biology, University of California, Santa Barbara, CA 93106, USA.
Biomed Res Int. 2014;2014:681396. doi: 10.1155/2014/681396. Epub 2014 Feb 23.
Phytoestrogens are produced by plants and may cause endocrine disruption in vertebrates. The present study hypothesizes that phytoestrogen exposure of female Siamese fighting fish (Betta splendens) may disrupt endogenous steroid levels, change agonistic behavior expression, and potentially also disrupt oocyte development. However, only the pharmacologic dose of β-sitosterol had a significant effect on opercular flaring behavior, while we did not find significant effects of β-sitosterol or genistein on steroids or gonads. These findings are in direct contrast with previous studies on the effects of phytoestrogens in female fish. Results of the current study support previous work showing that the effects of phytoestrogen exposure may be less acute in mature female B. splendens than in other fish.
植物雌激素由植物产生，可能会扰乱脊椎动物的内分泌。本研究假设，暹罗斗鱼（Betta splendens）雌鱼接触植物雌激素可能会扰乱内源性类固醇水平，改变争斗行为表现，还可能扰乱卵母细胞发育。然而，只有药理剂量的β-谷甾醇对鳃盖张合行为有显著影响，而我们未发现β-谷甾醇或染料木黄酮对类固醇或性腺有显著影响。这些发现与之前关于植物雌激素对雌鱼影响的研究结果直接相反。本研究结果支持了之前的研究工作，即成熟雌鱼接触植物雌激素的影响可能不如其他鱼类那样剧烈。
