Vedeler C A, Nilsen R, Matre R
Department of Oral Pathology and Forensic Odontology, University of Bergen, Norway.
J Neuroimmunol. 1989 Jun;23(1):29-33. doi: 10.1016/0165-5728(89)90069-6.
The localization of receptors for the Fc part of IgG (Fc gamma R) and for the complement C3b/C4b components (CR1) on human peripheral nerve fibres was investigated by indirect immunoperoxidase staining of frozen nerve sections with monoclonal antibodies. Transmission electron microscopy revealed that Fc gamma R and CR1 are localized to the entire surface membrane and inner membrane (axolemma) of the Schwann cell. Myelin and axons were not stained. The presence of Fc gamma R and CR1 in human Schwann cells adds further evidence for the immunocompetence of these cells.
