Benatar Jocelyne R, Stewart Ralph A H
Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand.
Nutr J. 2014 Apr 3;13:32. doi: 10.1186/1475-2891-13-32.
Dairy food is an important natural source of saturated and trans fatty acids in the human diet. This study evaluates the effect of dietary advice to change dairy food intake on plasma fatty acid levels known to be present in milk in healthy volunteers.
Twenty one samples of whole fat dairy milk were analyzed for fatty acids levels. Changes in levels of plasma phospholipid levels were evaluated in 180 healthy volunteers randomized to increase, not change or reduce dairy intake for one month. Fatty acids were measured by gas chromatography-mass spectrometry and levels are normalized to d-4 alanine.
The long chain fatty acids palmitic (13.4%), stearic (16.7%) and myristic (18.9%) acid were most common saturated fats in milk. Four trans fatty acids constituted 3.7% of the total milk fat content. Increased dairy food intake by 3.0 (± 1.2) serves/ day for 1 month was associated with small increases in plasma levels of myristic (+0.05, 95% confidence level-0.08 to 0.13, p = 0.07), pentadecanoic (+0.014, 95% confidence level -0.016 to 0.048, p = 0.02) and margaric acid (+0.02, -0.03 to 0.05, p = 0.03). There was no significant change in plasma levels of 4 saturated, 4 trans and 10 unsaturated fatty acids. Decreasing dairy food intake by 2.5 (± 1.2) serves per day was not associated with change in levels of any plasma fatty acid levels.
Dietary advice to change dairy food has a minor effect on plasma fatty acid levels.
ACTRN12612000574842.
乳制品是人类饮食中饱和脂肪酸和反式脂肪酸的重要天然来源。本研究评估了改变乳制品摄入量的饮食建议对健康志愿者血浆中已知存在于牛奶中的脂肪酸水平的影响。
分析了21份全脂牛奶样本的脂肪酸水平。对180名健康志愿者进行随机分组，分别增加、不变或减少乳制品摄入量，为期1个月，评估血浆磷脂水平的变化。通过气相色谱-质谱法测量脂肪酸，并将水平标准化为d-4丙氨酸。
长链脂肪酸棕榈酸（13.4%）、硬脂酸（16.7%）和肉豆蔻酸（18.9%）是牛奶中最常见的饱和脂肪。四种反式脂肪酸占总乳脂含量的3.7%。每天增加3.0（±1.2）份乳制品摄入量，持续1个月，与血浆肉豆蔻酸水平小幅升高（+0.05，95%置信区间-0.08至0.13，p = 0.07）、十五烷酸（+0.014，95%置信区间-0.016至0.048，p = 0.02）和十七烷酸（+0.02，-0.03至0.05，p = 0.03）有关。4种饱和脂肪酸、4种反式脂肪酸和10种不饱和脂肪酸的血浆水平无显著变化。每天减少2.5（±1.2）份乳制品摄入量与任何血浆脂肪酸水平的变化均无关。
改变乳制品摄入量的饮食建议对血浆脂肪酸水平影响较小。
ACTRN12612000574842。
