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尽管尼泊尔城市哺乳期妇女从饮食中摄入铁不足的风险很高,但缺铁情况并不常见。

Iron deficiency is uncommon among lactating women in urban Nepal, despite a high risk of inadequate dietary iron intake.

作者信息

Henjum Sigrun, Manger Mari, Skeie Eli, Ulak Manjeswori, Thorne-Lyman Andrew L, Chandyo Ram, Shrestha Prakash S, Locks Lindsey, Ulvik Rune J, Fawzi Wafaie W, Strand Tor A

机构信息

Oslo and Akershus University College of Applied Sciences,PO Box 4, St Olavs Plass,N-0130Oslo,Norway.

Centre for International Health, University of Bergen,PO Box 7800,5020Bergen,Norway.

出版信息

Br J Nutr. 2014 Jul 14;112(1):132-41. doi: 10.1017/S0007114514000592. Epub 2014 Apr 8.

Abstract

The main objective of the present study was to examine the association between dietary Fe intake and dietary predictors of Fe status and Hb concentration among lactating women in Bhaktapur, Nepal. We included 500 randomly selected lactating women in a cross-sectional survey. Dietary information was obtained through three interactive 24 h recall interviews including personal recipes. Concentrations of Hb and plasma ferritin and soluble transferrin receptors were measured. The daily median Fe intake from food was 17·5 mg, and 70% of the women were found to be at the risk of inadequate dietary Fe intake. Approximately 90% of the women had taken Fe supplements in pregnancy. The prevalence of anaemia was 20% (Hb levels < 123 g/l) and that of Fe deficiency was 5% (plasma ferritin levels < 15 μg/l). In multiple regression analyses, there was a weak positive association between dietary Fe intake and body Fe (β 0·03, 95% CI 0·014, 0·045). Among the women with children aged < 6 months, but not those with older infants, intake of Fe supplements in pregnancy for at least 6 months was positively associated with body Fe (P for interaction < 0·01). Due to a relatively high dietary intake of non-haem Fe combined with low bioavailability, a high proportion of the women in the present study were at the risk of inadequate intake of Fe. The low prevalence of anaemia and Fe deficiency may be explained by the majority of the women consuming Fe supplements in pregnancy.

摘要

本研究的主要目的是调查尼泊尔巴克塔普尔哺乳期妇女的膳食铁摄入量与铁状态及血红蛋白浓度的膳食预测指标之间的关联。我们在一项横断面调查中纳入了500名随机选取的哺乳期妇女。通过三次包括个人食谱的24小时互动回顾访谈获取膳食信息。测量了血红蛋白、血浆铁蛋白和可溶性转铁蛋白受体的浓度。食物中的每日铁摄入量中位数为17.5毫克,发现70%的妇女存在膳食铁摄入不足的风险。约90%的妇女在孕期服用了铁补充剂。贫血患病率为20%(血红蛋白水平<123克/升),缺铁患病率为5%(血浆铁蛋白水平<15微克/升)。在多元回归分析中,膳食铁摄入量与体内铁之间存在微弱的正相关(β 0.03,95%可信区间0.014,0.045)。在有6个月以下婴儿的妇女中,而非有较大婴儿的妇女中,孕期铁补充剂摄入至少6个月与体内铁呈正相关(交互作用P<0.01)。由于非血红素铁的膳食摄入量相对较高且生物利用度低,本研究中很大一部分妇女存在铁摄入不足的风险。贫血和缺铁的低患病率可能是由于大多数妇女在孕期服用了铁补充剂。

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