2型糖尿病成人患者感觉功能和力量产生的变化。
Changes in sensory function and force production in adults with type II diabetes.
作者信息
Ochoa Nereyda, Gorniak Stacey L
机构信息
Department of Health and Human Performance, University of Houston, 3855 Holman Street, Garrison 104U, Houston, Texas, 77204, USA; Center for Neuromotor and Biomechanics Research, University of Houston, Houston, Texas, USA.
出版信息
Muscle Nerve. 2014 Dec;50(6):984-90. doi: 10.1002/mus.24261. Epub 2014 Oct 30.
INTRODUCTION
The purpose of this study was to evaluate the relationship among sensory function, disease severity, and upper extremity force production in adults with type II diabetes (T2D) as compared with healthy age- and gender-matched controls.
METHODS
Ten adults with T2D and 10 healthy age- and gender-matched control subjects underwent a battery of sensory and motor function evaluations. Data on disease severity and duration were also collected.
RESULTS
The T2D group exhibited sensory deficits and altered force production as compared with healthy controls. Sensory function correlated with disease severity, as did signal predictability of kinetic output during submaximal force production tasks. Maximal force production tasks were associated with altered output in T2D, but these data did not correlate with disease severity or sensory dysfunction.
CONCLUSIONS
Some, not all, motor performance deficits in T2D are associated with sensory dysfunction. Mechanisms responsible for these changes in adult-onset T2D are described.
引言
本研究旨在评估成年2型糖尿病（T2D）患者与年龄和性别匹配的健康对照者相比，其感觉功能、疾病严重程度和上肢力量产生之间的关系。
方法
10名成年T2D患者和10名年龄和性别匹配的健康对照者接受了一系列感觉和运动功能评估。还收集了疾病严重程度和病程的数据。
结果
与健康对照者相比，T2D组表现出感觉缺陷和力量产生改变。感觉功能与疾病严重程度相关，次最大力量产生任务期间动力学输出的信号可预测性也与疾病严重程度相关。最大力量产生任务与T2D患者的输出改变有关，但这些数据与疾病严重程度或感觉功能障碍无关。
结论
T2D患者的部分而非全部运动表现缺陷与感觉功能障碍有关。描述了成年发病T2D中这些变化的相关机制。
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