Research Division Institute of Mental Health, Buangkok Green Medical Park, 10 Buangkok View, Singapore 539747.
Gen Hosp Psychiatry. 2014 Jul-Aug;36(4):375-81. doi: 10.1016/j.genhosppsych.2014.03.002. Epub 2014 Mar 12.
The objective was to establish the prevalence and risk factors for multiple chronic medical conditions (MCMC) in the Singapore population.
Data for the study were extracted from the Singapore Mental Health Study, a population-based, cross-sectional, epidemiological study of Singapore residents aged 18 years and above. Face-to-face interviews were completed with 6616 respondents from December 2009 to December 2010, and the survey response rate was 75.9%. The assessment of psychiatric conditions was established using version 3.0 of the WHO World Mental Health Composite International Diagnostic Interview (WMH-CIDI). A modified version of the CIDI checklist of chronic medical conditions was used to capture data on 15 chronic medical conditions which were reclassified into eight types of physical conditions.
A total of 25.4% of the population reported having one chronic condition, and 16.3% had MCMC. Those who were older (aged 35 years and above vs. those aged 18-34 years), economically inactive, unemployed, overweight and obese had higher odds of having MCMC. Adjusting for covariates in multinomial regression analyses, mood and alcohol use disorder (AUD) were significantly associated with higher risk of MCMC.
The study identified two important yet potentially modifiable risk factors for MCMC--psychiatric conditions and obesity--in the general population. Screening for mood and alcohol use disorder, as well as lifestyle interventions targeted at obesity, must be a part of disease management for MCMC.
本研究旨在确定新加坡人群中多种慢性疾病(MCMC)的患病率和相关风险因素。
本研究的数据来自新加坡心理健康研究,这是一项针对新加坡 18 岁及以上居民的基于人群的横断面流行病学研究。2009 年 12 月至 2010 年 12 月期间,对 6616 名受访者进行了面对面访谈,调查的回复率为 75.9%。采用世界卫生组织(WHO)精神卫生综合国际诊断访谈(WMH-CIDI)第 3.0 版评估精神疾病状况。采用 CIDI 慢性疾病清单的修改版本,记录了 15 种慢性疾病的数据,这些疾病被重新分类为 8 种身体状况类型。
研究人群中,25.4%的人报告有一种慢性疾病,16.3%的人患有 MCMC。年龄较大(35 岁及以上比 18-34 岁)、经济不活跃、失业、超重和肥胖的人患有 MCMC 的几率更高。在多变量回归分析中调整了协变量后,情绪和酒精使用障碍(AUD)与 MCMC 的风险显著相关。
本研究在普通人群中确定了两种重要但潜在可改变的 MCMC 风险因素——精神疾病和肥胖。对情绪和酒精使用障碍进行筛查,以及针对肥胖的生活方式干预,必须成为 MCMC 疾病管理的一部分。