Tzardi Maria, Papadakis Michael, Giannikaki Elpida, Datseri Galatia, Kouroumalis Elias A, Kalogeraki Alexandra
Departments of Pathology (Maria Tzardi, Michael Papadakis, Elpida Giannikaki, Galatia Datseri, Alexandra Kalogeraki).
Gastroenterology (Elias A. Kouroumalis) University of Crete.
Ann Gastroenterol. 2011;24(3):222-224.
the first case concerns a 73-year-old male patient with clinical history of cardiovascular disease and pulmonary insufficiency, admitted to the hospital for urinary tract infection and was treated with broad-spectrum antibiotics for a long period of time. During his hospitalization he developed abdominal pain and haematochezia. The second case concerns a 64-year-old woman treated with antibiotics for community-acquired pneumonia. After the treatment she developed abdominal pain and diarrhea. In both cases the colonic biopsy showed pseudomembranous colitis with presence of signet-ring cells within dilated crypts of the colonic mucosa. The presence of signet-ring cells is a rare finding in pseudomembranous colitis and may lead to misdiagnosis of signet-ring carcinoma of the colon.
首例病例为一名73岁男性患者，有心血管疾病和肺功能不全病史，因尿路感染入院并长期接受广谱抗生素治疗。住院期间，他出现腹痛和便血。第二例病例为一名64岁女性，因社区获得性肺炎接受抗生素治疗。治疗后，她出现腹痛和腹泻。两例病例的结肠活检均显示为假膜性结肠炎，在结肠黏膜扩张的隐窝内可见印戒细胞。印戒细胞在假膜性结肠炎中是一种罕见的发现，可能导致结肠印戒细胞癌的误诊。
