Jolly Stacey E, Navaneethan Sankar D, Schold Jesse D, Arrigain Susana, Sharp John W, Jain Anil K, Schreiber Martin J, Simon James F, Nally Joseph V
Department of General Internal Medicine, Medicine Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Am J Nephrol. 2014;39(4):288-96. doi: 10.1159/000360306. Epub 2014 Apr 1.
Whether chronic kidney disease (CKD) recognition in an electronic health record (EHR) problem list improves processes of care or clinical outcomes of end-stage renal disease (ESRD) and death is unclear.
We identified patients who had at least 1 year of follow-up (2005-2009) in our EHR-based CKD registry (n = 25,742). CKD recognition was defined by having ICD-9 codes for CKD, diabetic kidney disease, or hypertensive kidney disease in the problem list. We calculated proportions of patients with and without CKD recognition and examined differences by demographics, clinical factors, and development of ESRD or mortality. We evaluated differences in the proportion of patients with CKD-specific laboratory results checked before and after recognition among cases and propensity-matched controls.
Only 11% (n = 2,735) had CKD recognition in the problem list and they were younger (68 vs. 71 years), a higher proportion were male (61 vs. 37%) and African-American (21 vs. 10%) compared to those unrecognized. CKD-specific laboratory results for patients with estimated glomerular filtration rate (eGFR) 30-59 including intact parathyroid hormone (23 vs. 6%), vitamin D (22 vs. 18%), phosphorus (29 vs. 7%), and a urine check for proteinuria (55 vs. 36%) were significantly more likely to be done among those with CKD recognition (all p < 0.05). Similar results were found for eGFR <30 except for proteinuria and in our propensity score-matched control analysis. There was no independent association of CKD recognition with ESRD or mortality.
CKD recognition in the EHR problem list was low, but translated into more CKD-specific processes of care; however ESRD or mortality were not affected.
电子健康记录(EHR)问题列表中对慢性肾脏病(CKD)的识别是否能改善护理流程或终末期肾病(ESRD)及死亡的临床结局尚不清楚。
我们在基于EHR的CKD登记系统中识别出至少有1年随访时间(2005 - 2009年)的患者(n = 25,742)。CKD识别定义为问题列表中有CKD、糖尿病肾病或高血压肾病的ICD - 9编码。我们计算了有和没有CKD识别的患者比例,并按人口统计学、临床因素以及ESRD或死亡率的发展情况进行差异分析。我们评估了病例组和倾向匹配对照组中识别前后进行CKD特异性实验室检查的患者比例差异。
问题列表中仅有11%(n = 2,735)的患者有CKD识别,与未被识别的患者相比,他们更年轻(68岁对71岁),男性比例更高(61%对37%),非裔美国人比例更高(21%对10%)。估算肾小球滤过率(eGFR)为30 - 59的患者中,有CKD识别的患者进行CKD特异性实验室检查的可能性显著更高,包括完整甲状旁腺激素(23%对6%)、维生素D(22%对18%)、磷(29%对7%)以及蛋白尿尿液检查(55%对36%)(所有p < 0.05)。对于eGFR < 30的患者,除蛋白尿外,在我们的倾向得分匹配对照分析中也发现了类似结果。CKD识别与ESRD或死亡率无独立关联。
EHR问题列表中CKD识别率较低,但能转化为更多的CKD特异性护理流程;然而,ESRD或死亡率未受影响。