Sindjelic R P, Vlajkovic G P, Lucic M, Koncar I, Kostic D, Davidovic L B
Faculty of Medicine, University of Belgrade Belgrade, Serbia -
J Cardiovasc Surg (Torino). 2015 Jun;56(3):441-6. Epub 2014 Apr 8.
He aim of this paper was to investigate the incidence of and the indications for conversion to general anesthesia (GA) in a large single-center series of patients undergoing carotid surgery under cervical plexus block (CPB).
With IRB approval we retrospectively analyzed the medical records of all patients who underwent carotid surgery under CPB from November 2007 to October 2010. Cervical plexus was blocked at both the superficial and deep levels. An intraluminal shunt was inserted in patients who demonstrated signs of inadequate cerebral perfusion upon carotid clamping (CC). Propofol was given to patients reporting pain or discomfort throughout the procedure. The primary outcomes were the number and percentage of conversions to GA as well as the indications for this intervention. The secondary outcome was the incidence of partial cervical block failure, defined as the need for supplemental propofol administration for pain relief during surgery.
In total, 1464 carotid surgical procedures were performed under CPB in 1305 consecutive patients during the investigated period. Conversion to GA was required in 17 (1.2%) patients. The most common reason for conversion to GA was persisting neurological deterioration upon CC and intraluminal shunt insertion, which was recorded in 8/17 (47.1%) procedures. Other indications to convert were systemic toxicity of local anesthetics, pain, general discomfort and restlessness during surgery, and acute myocardial infarction.
Cervical plexus block for carotid surgery is associated with a low rate of conversions to GA. Neurological deterioration upon carotid clamping and local anesthetic toxicity are identified as the most common indications for such intervention.
本文旨在调查在一个大型单中心系列接受颈丛阻滞(CPB)下行颈动脉手术的患者中,转为全身麻醉(GA)的发生率及指征。
经机构审查委员会(IRB)批准,我们回顾性分析了2007年11月至2010年10月期间所有接受CPB下行颈动脉手术患者的病历。颈丛在浅、深两层均进行阻滞。对于在颈动脉夹闭(CC)时出现脑灌注不足迹象的患者,插入腔内分流管。在整个手术过程中,对报告疼痛或不适的患者给予丙泊酚。主要结局是转为GA的例数和百分比以及这种干预的指征。次要结局是部分颈丛阻滞失败的发生率,定义为手术期间需要补充丙泊酚以缓解疼痛。
在研究期间,连续1305例患者共进行了1464例CPB下的颈动脉手术。17例(1.2%)患者需要转为GA。转为GA最常见的原因是CC和插入腔内分流管后持续的神经功能恶化,在17例手术中有8例(47.1%)记录为此种情况。其他转为GA的指征包括局部麻醉药的全身毒性、疼痛、手术期间的一般不适和躁动以及急性心肌梗死。
颈动脉手术的颈丛阻滞转为GA的发生率较低。颈动脉夹闭时的神经功能恶化和局部麻醉药毒性被确定为这种干预最常见的指征。