Department of Neurosurgery, Iowa Spine and Brain Institute, Waterloo, IA, USA,
J Neurooncol. 2014 Jul;118(3):435-60. doi: 10.1007/s11060-013-1330-0. Epub 2014 Apr 9.
Which imaging techniques most accurately differentiate true tumor progression from pseudo-progression or treatment related changes in patients with previously diagnosed glioblastoma?
These recommendations apply to adults with previously diagnosed glioblastoma who are suspected of experiencing progression of the neoplastic process.
Magnetic resonance imaging with and without gadolinium enhancement is recommended as the imaging surveillance method to detect the progression of previously diagnosed glioblastoma.
Magnetic resonance spectroscopy is recommended as a diagnostic method to differentiate true tumor progression from treatment-related imaging changes or pseudo-progression in patients with suspected progressive glioblastoma.
The routine use of positron emission tomography to identify progression of glioblastoma is not recommended.
Single-photon emission computed tomography imaging is recommended as a diagnostic method to differentiate true tumor progression from treatment-related imaging changes or pseudo-progression in patients with suspected progressive glioblastoma.
哪些影像学技术最能准确地区分真性肿瘤进展与复发性胶质母细胞瘤患者中的假性进展或治疗相关变化？
这些建议适用于先前诊断为胶质母细胞瘤且疑似肿瘤进展的成人患者。
建议等级 II：建议使用磁共振成像（MRI）联合或不联合钆增强作为影像学监测方法，以检测先前诊断的胶质母细胞瘤的进展。
等级 II：建议磁共振波谱分析作为一种诊断方法，以区分疑似进展性胶质母细胞瘤患者中的真性肿瘤进展与治疗相关的影像学改变或假性进展。
等级 III：不建议常规使用正电子发射断层扫描（PET）来识别胶质母细胞瘤的进展。
等级 III：建议单光子发射计算机断层扫描（SPECT）成像作为一种诊断方法，以区分疑似进展性胶质母细胞瘤患者中的真性肿瘤进展与治疗相关的影像学改变或假性进展。
