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一例腰椎痛风石性痛风:文献综述与治疗建议

A case of tophaceous gout in the lumbar spine: a review of the literature and treatment recommendations.

作者信息

Jegapragasan Mithulan, Calniquer Alejandro, Hwang William D, Nguyen Quynh T, Child Zachary

机构信息

Department of Orthopaedics and Sports Medicine, University of Washington, Seattle, United States.

Department of Radiology, University of Washington, Seattle, United States.

出版信息

Evid Based Spine Care J. 2014 Apr;5(1):52-6. doi: 10.1055/s-0034-1366979.

Abstract

Study Design Case report. Objective The objective of this study is to report the occurrence of tophaceous gout in the lumbar spine. Methods Using a case report to illustrate the key points of gout in the spine, we provide a brief review of gout in the literature as it relates to its orthopedic and spinal manifestations as well as guidelines for management. Results This case report details the occurrence of a large and clinically significant finding of tophaceous gout in the lumbar spine in a 24-year-old man with a known history of gout and a 3-year history of progressive back pain. Conclusion A high index of suspicion can assist in diagnosis of patients presenting with back pain or neurologic findings with a history of gout. A previous history of gout (especially the presence of tophi), hyperuricemia, and the radiological characteristics presented here should aid the clinician in making the diagnosis of spinal gout. Early diagnosis has the potential to prevent the need for surgical intervention.

摘要

研究设计 病例报告。目的 本研究的目的是报告腰椎部位痛风石性痛风的发生情况。方法 通过一个病例报告来说明脊柱痛风的要点,我们对文献中痛风与骨科及脊柱表现的关系以及管理指南进行了简要回顾。结果 本病例报告详细描述了一名24岁有痛风病史且有3年进行性背痛病史的男性患者腰椎部位出现的一个大的且具有临床意义的痛风石性痛风表现。结论 高度的怀疑指数有助于诊断有痛风病史且出现背痛或神经系统症状的患者。痛风病史(尤其是痛风石的存在)、高尿酸血症以及此处呈现的放射学特征应有助于临床医生诊断脊柱痛风。早期诊断有可能避免手术干预的需要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15d7/3969431/80c98be07394/10-1055-s-0034-1366979-i1300029cr-1.jpg

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