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用于生物分子检测的高性能导电聚合物纳米纤维生物传感器。

High performance conducting polymer nanofiber biosensors for detection of biomolecules.

作者信息

Yang Guang, Kampstra Kelly L, Abidian Mohammad Reza

机构信息

Department of Biomedical Engineering, Pennsylvania State University, University Park, PA, 16802, USA.

出版信息

Adv Mater. 2014 Aug 6;26(29):4954-60. doi: 10.1002/adma.201400753. Epub 2014 Apr 9.

Abstract

Sensitive detection and selective determination of the physiologically important chemicals involved in brain function have drawn much attention for the diagnosis and treatment of brain diseases and neurological disorders. This paper reports a novel method for fabrication of enzyme entrapped-conducting polymer nanofibers that offer higher sensitivity and increased lifetime compared to glucose sensors that are based on conducting polymer films.

摘要

对参与脑功能的生理重要化学物质进行灵敏检测和选择性测定,在脑部疾病和神经紊乱的诊断与治疗方面引起了广泛关注。本文报道了一种制备酶包埋导电聚合物纳米纤维的新方法,与基于导电聚合物薄膜的葡萄糖传感器相比,该方法具有更高的灵敏度和更长的使用寿命。

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