Bando Harumi, Sugiura Hiroaki, Ohkusa Yasushi, Akahane Manabu, Sano Tomomi, Jojima Noriko, Okabe Nobuhiko, Imamura Tomoaki
a Faculty of Nursing , Nara Medical University , Kashihara , Japan.
Int J Environ Health Res. 2015;25(1):104-13. doi: 10.1080/09603123.2014.903904. Epub 2014 Apr 10.
Cedar pollinosis in Japan affects nearly 25 % of Japanese citizens. To develop a treatment for cedar pollinosis, it is necessary to understand the relationship between the time of its occurrence and the amount of airborne cedar pollen. In the spring of 2009, we conducted daily Internet-based epidemiologic surveys, which included 1453 individuals. We examined the relationship between initial date of onset of pollinosis symptoms and daily amount of airborne cedar pollen to which subjects were exposed. Approximately 35.2 % of the subjects experienced the onset of pollinosis during a one-week interval in which the middle day coincided with the peak pollen count. The odds ratio for this one-week time interval was 4.03 (95 % confidence interval: 3.34-4.86). The predicted date of the cedar pollen peak can be used to determine the appropriate date for initiation of self-medication with anti-allergy drugs and thus avoid development of sustained and severe pollinosis.
日本的雪松花粉症影响了近25%的日本公民。为了开发雪松花粉症的治疗方法，有必要了解其发病时间与空气中雪松花粉量之间的关系。2009年春天，我们开展了每日基于互联网的流行病学调查，调查对象包括1453人。我们研究了花粉症症状的初始发病日期与受试者接触的空气中雪松花粉每日量之间的关系。约35.2%的受试者在中间日期与花粉计数峰值重合的一周时间间隔内出现花粉症发病。这一周时间间隔的优势比为4.03（95%置信区间：3.34 - 4.86）。雪松花粉峰值的预测日期可用于确定开始自我服用抗过敏药物的合适日期，从而避免持续性严重花粉症的发生。
