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Regulation of rat liver acute phase genes by interleukin-6 and production of hepatocyte stimulating factors by rat hepatoma cells.

作者信息

Fey G H, Hattori M, Northemann W, Abraham L J, Baumann M, Braciak T A, Fletcher R G, Gauldie J, Lee F, Reymond M F

机构信息

Department of Immunology, Research Institute of Scripps Clinic, La Jolla, California 92037.

出版信息

Ann N Y Acad Sci. 1989;557:317-29; discussion 329-31. doi: 10.1111/j.1749-6632.1989.tb24024.x.

DOI:10.1111/j.1749-6632.1989.tb24024.x
PMID:2472092
Abstract
摘要

相似文献

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Regulation of rat liver acute phase genes by interleukin-6 and production of hepatocyte stimulating factors by rat hepatoma cells.白细胞介素-6对大鼠肝脏急性期基因的调控以及大鼠肝癌细胞产生肝细胞刺激因子的研究。
Ann N Y Acad Sci. 1989;557:317-29; discussion 329-31. doi: 10.1111/j.1749-6632.1989.tb24024.x.
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Interleukin-6. The major regulator of acute-phase protein synthesis in man and rat.白细胞介素-6。人和大鼠急性期蛋白合成的主要调节因子。
Ann N Y Acad Sci. 1989;557:87-99; discussion 100-1.
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Response of liver genes to acute phase mediators.
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Acute-phase reaction induces a specific complex between hepatic nuclear proteins and the interleukin 6 response element of the rat alpha 2-macroglobulin gene.急性期反应诱导肝细胞核蛋白与大鼠α2-巨球蛋白基因的白细胞介素6反应元件之间形成一种特异性复合物。
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Phorbol ester modulates interleukin 6- and interleukin 1-regulated expression of acute phase plasma proteins in hepatoma cells.佛波酯调节肝癌细胞中白细胞介素6和白细胞介素1调控的急性期血浆蛋白的表达。
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Cell-free-synthesized interleukin-6 (BSF-2/IFN-beta 2) exhibits hepatocyte-stimulating activity.无细胞合成的白细胞介素-6（BSF-2/干扰素-β2）具有刺激肝细胞的活性。
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Effects of HGF and RA on the class 1 and class 2 rat acute phase proteins.肝细胞生长因子和视黄酸对大鼠1类和2类急性期蛋白的影响。
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Mammary gland factor activated by prolactin on mammary epithelial cells and acute-phase response factor activated by interleukin-6 in liver cells share DNA binding and transactivation potential.催乳素激活的乳腺上皮细胞中的乳腺因子和白细胞介素-6激活的肝细胞中的急性期反应因子具有共同的DNA结合和反式激活潜能。
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Autocrine activity of interleukin 6 secreted by hepatocarcinoma cell lines.肝癌细胞系分泌的白细胞介素6的自分泌活性。
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IFN beta 2/IL-6 is one of several cytokines that modulate acute phase gene expression in human hepatocytes and human macrophages.
Ann N Y Acad Sci. 1989;557:332-41; discussion 341-2.

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Metallothionein induction in cultured rat hepatocytes by arthritic rat serum, activated macrophages, interleukin-6, interleukin-11 and leukaemia inhibitory factor.关节炎大鼠血清、活化巨噬细胞、白细胞介素-6、白细胞介素-11和白血病抑制因子对培养大鼠肝细胞金属硫蛋白的诱导作用。
Inflamm Res. 1995 Nov;44(11):475-81. doi: 10.1007/BF01837913.
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J Exp Med. 1994 Oct 1;180(4):1243-50. doi: 10.1084/jem.180.4.1243.
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Structure, hormonal regulation, and identification of the interleukin-6- and dexamethasone-responsive element of the rat haptoglobin gene.大鼠触珠蛋白基因白细胞介素-6和地塞米松反应元件的结构、激素调节及鉴定
Mol Cell Biol. 1990 Apr;10(4):1573-83. doi: 10.1128/mcb.10.4.1573-1583.1990.
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A 58-base-pair region of the human C3 gene confers synergistic inducibility by interleukin-1 and interleukin-6.人类C3基因的一个58个碱基对的区域可通过白细胞介素-1和白细胞介素-6产生协同诱导作用。
Mol Cell Biol. 1990 Dec;10(12):6181-91. doi: 10.1128/mcb.10.12.6181-6191.1990.
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Distinct regulation of the interleukin-1 and interleukin-6 response elements of the rat haptoglobin gene in rat and human hepatoma cells.大鼠触珠蛋白基因白细胞介素-1和白细胞介素-6反应元件在大鼠和人肝癌细胞中的不同调控
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An inducible 50-kilodalton NF kappa B-like protein and a constitutive protein both bind the acute-phase response element of the angiotensinogen gene.一种可诱导的50千道尔顿的核因子κB样蛋白和一种组成型蛋白均能结合血管紧张素原基因的急性期反应元件。
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Acute-phase reaction induces a specific complex between hepatic nuclear proteins and the interleukin 6 response element of the rat alpha 2-macroglobulin gene.急性期反应诱导肝细胞核蛋白与大鼠α2-巨球蛋白基因的白细胞介素6反应元件之间形成一种特异性复合物。
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