Dmitriev A D, Chirkova S K, Dmitrieva O F, Tennov A V, Shchurin M R
Biull Eksp Biol Med. 1989 May;107(5):572-4.
Daily administration of 12 mg of dexamethasone to monkeys during 10 days resulted in decrease of the levels of alpha- and gamma-endorphins and cortisol 7 days after the first injection. The titers of these peptides in plasma of monkeys. exposed to two hours of immobilization stress were elevated twice above basal levels. The maximum elevation took place 6 hours after the beginning of immobilization. This effect wasn't detected in monkeys, which received 12 mg of dexamethasone during 10 days.
在10天内每天给猴子注射12毫克地塞米松，在首次注射7天后，α-内啡肽、γ-内啡肽和皮质醇水平降低。暴露于两小时固定应激的猴子血浆中这些肽的滴度比基础水平升高了两倍。最大升高发生在固定开始后6小时。在10天内接受12毫克地塞米松的猴子中未检测到这种效应。
