Konar Karabi, Sanyal Saurabh, Rakshit Arindam
Department of Pathology, Burdwan Medical College, Burdwan, West Bengal, India.
Indian J Ophthalmol. 2014 Mar;62(3):361-3. doi: 10.4103/0301-4738.121142.
Annular elastolytic giant cell granuloma is a condition characterized histologically by damaged elastic fibers associated with preponderance of giant cells along with absence of necrobiosis, lipid, mucin, and pallisading granuloma. It usually occurs on sun-damaged skin and hence the previous name actinic granuloma. A similar process occurs on the conjunctiva. Over the past three decades only four cases of conjunctival actinic granuloma have been documented. All the previous patients were females with lesions in nasal or temporal bulbar conjunctiva varying 2-3 mm in size. We report a male patient aged 70 years presenting with a 14 mm × 7 mm fleshy mass on right lower bulbar conjunctiva. Clinical differential diagnoses were lymphoma, squamous cell carcinoma in situ and amyloidosis. Surgical excision followed by histopathology confirmed it to be a case of actinic granuloma. This is the first case of isolated conjunctival actinic granuloma of such a large size reported from India.
环状弹性组织溶解性巨细胞肉芽肿是一种组织学上以弹性纤维受损为特征的疾病,伴有大量巨细胞,且无渐进性坏死、脂质、黏液和栅栏状肉芽肿。它通常发生在受阳光损伤的皮肤上,因此以前称为光化性肉芽肿。类似的过程也发生在结膜上。在过去三十年中,仅有4例结膜光化性肉芽肿的病例被记录。之前所有患者均为女性,病变位于鼻侧或颞侧球结膜,大小为2 - 3毫米。我们报告一例70岁男性患者,其右下球结膜出现一个14毫米×7毫米的肉质肿物。临床鉴别诊断包括淋巴瘤、原位鳞状细胞癌和淀粉样变性。手术切除后经组织病理学证实为光化性肉芽肿病例。这是印度报道的首例如此大尺寸的孤立性结膜光化性肉芽肿病例。