Dell'osso Liliana, Carmassi Claudia, Rucci Paola, Ciapparelli Antonio, Conversano Ciro, Marazziti Donatella
CNS Spectr. 2011 Jan;16(1):1-6. doi: 10.1017/S1092852912000090.
IntroductionThe aim of the present study was to explore the relationship between subthreshold mood symptoms and suicidality in patients with complicated grief (CG).
Fifty patients with CG were included in the study and evaluated by the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Axis-I disorders, the Inventory of Complicated Grief, and the Mood Spectrum Self Report (MOODS-SR) lifetime version, to evaluate the subthreshold mood symptoms.
Twenty-eight patients (56%) reported lifetime suicidal ideation and 11 patients (22%) reported suicide attempts. Subthreshold depressive and rhythmicity/vegetative functions items of the MOODS-SR were significantly associated with increased suicidal ideation and attempts, while subthreshold manic items were associated with suicidal ideation only. Relationships were confirmed after controlling for Axis-I disorders comorbidity.
The results of the present study suggest the usefulness of exploring lifetime subthreshold mood symptoms in CG patients, in order to promptly identify those who may be more prone to suicidality.
引言
本研究的目的是探讨复杂性哀伤(CG)患者阈下情绪症状与自杀倾向之间的关系。
本研究纳入了50名CG患者,并通过《精神障碍诊断与统计手册》第四版轴I障碍的结构化临床访谈、复杂性哀伤量表以及心境谱自评量表(MOODS-SR)终生版对阈下情绪症状进行评估。
28名患者(56%)报告有终生自杀观念,11名患者(22%)报告有自杀未遂。MOODS-SR的阈下抑郁及节律/植物神经功能项目与自杀观念及自杀未遂的增加显著相关,而阈下躁狂项目仅与自杀观念相关。在控制轴I障碍共病后,这种关系得到了证实。
本研究结果表明,探索CG患者的终生阈下情绪症状有助于及时识别那些更易出现自杀倾向的患者。