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升主动脉到降主动脉旁路术:一个复杂问题的简单解决方案。

Ascending-to-descending aortic bypass: a simple solution to a complex problem.

机构信息

Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.

Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.

出版信息

Ann Thorac Surg. 2014 Jun;97(6):2041-7; discussion 2047-8. doi: 10.1016/j.athoracsur.2014.02.030. Epub 2014 Apr 12.

Abstract

BACKGROUND

Surgical correction of complex aortic coarctation can be associated with significant risks. Extraanatomic bypass may represent a safer alternative.

METHODS

Between January 1985 and December 2012, 80 consecutive patients with complex coarctation underwent ascending-to-descending aortic bypass through a median sternotomy. Patients were a median age of 42 years (range, 15 to 75 years), and 51 (64%) were males. Recurrent coarctation was present in 52 patients (65%), with 6 (8%) having undergone balloon dilatation. Uncontrolled hypertension was present in 63 patients (79%). The most common concomitant pathology was aortic valve stenosis in 21 patients (26%), subaortic stenosis in 10 (13%), and Shone complex in 4 (5%).

RESULTS

There were no early deaths. The most common concomitant procedures were aortic valve replacement, coronary artery bypass grafting, and resection of subaortic stenosis. The mean aortic cross-clamp and cardiopulmonary bypass times were 33 ± 40 and 106 ± 54 minutes, respectively. Morbidity included atrial fibrillation in 17 patients (21%) and reexploration for bleeding in 6 (8%). There was no paraplegia or stroke. Upper extremity blood pressure significantly improved (p < 0.001). Mean systolic blood pressure decreased from 153 ± 26 mm Hg preoperatively to 123 ± 15 mm Hg postoperatively. Mean follow-up was 7 ± 6 years (maximum, 22 years). Late deaths occurred in 5 patients (6%) and were not graft-related. Three patients (4%) required reoperation for repair of periprosthetic regurgitation in 2 and mitral valve replacement in 1.

CONCLUSIONS

The ascending-to-descending aortic bypass can be performed with low morbidity and mortality. It is an effective solution to complex aortic coarctation and represents a safe single-stage approach for patients with concomitant cardiac pathology.

摘要

背景

复杂主动脉缩窄的手术矫正可能会带来重大风险。体外旁路术可能是一种更安全的选择。

方法

1985 年 1 月至 2012 年 12 月期间,80 例连续的复杂主动脉缩窄患者通过正中胸骨切开术接受了升主动脉至降主动脉旁路术。患者的中位年龄为 42 岁(范围 15 至 75 岁),51 例(64%)为男性。52 例(65%)存在复发性主动脉缩窄,其中 6 例(8%)曾行球囊扩张术。63 例(79%)存在未控制的高血压。最常见的合并症为 21 例(26%)主动脉瓣狭窄、10 例(13%)主动脉瓣下狭窄和 4 例(5%)Shone 复合畸形。

结果

无早期死亡。最常见的合并手术为主动脉瓣置换术、冠状动脉旁路移植术和主动脉瓣下狭窄切除术。主动脉阻断和体外循环时间的平均值分别为 33 ± 40 分钟和 106 ± 54 分钟。并发症包括 17 例(21%)心房颤动和 6 例(8%)出血再次探查。无截瘫或中风。上肢血压显著改善(p < 0.001)。术前收缩压从 153 ± 26mmHg 降至术后的 123 ± 15mmHg。平均随访时间为 7 ± 6 年(最长 22 年)。5 例(6%)患者发生晚期死亡,与移植物无关。3 例(4%)患者因 2 例人工瓣周漏和 1 例二尖瓣置换需再次手术。

结论

升主动脉至降主动脉旁路术可在低发病率和死亡率的情况下进行。它是治疗复杂主动脉缩窄的有效方法,也是伴有心脏病变患者安全的单一阶段治疗方法。

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