Myers Russell B, Millman Brandon, Noor Mohamed A F
NorthgateArinso Human Resources, South Melbourne, VIC, 3205 Australia.
Pratt School of Engineering, Duke University, Durham, North Carolina 27708.
G3 (Bethesda). 2014 Apr 11;4(5):779-81. doi: 10.1534/g3.114.010215.
Students in college courses struggle to understand many concepts fundamental to transmission and evolutionary genetics, including multilocus inheritance, recombination, Hardy-Weinberg, and genetic drift. These students consistently ask for more demonstrations and more practice problems. With this demand in mind, the "Genetics and Evolution" app was designed to help students (and their instructors) by providing a suite of tools granting them the ability to: (1) simulate genetic crosses with varying numbers of genes and patterns of inheritance, (2) simulate allele frequency changes under natural selection and/ or genetic drift, (3) quiz themselves to reinforce terminology (customizable by any instructor for their whole classroom), *4) solve various problems (recombination fractions, Hardy-Weinberg, heritability, population growth), and (5) generate literally an infinite number of practice problems in all of these areas to try on their own. Although some of these functions are available elsewhere, the alternatives do not have the ability to instantly generate new practice problems or achieve these diverse functions in devices that students carry in their pockets every day.
大学课程中的学生很难理解许多遗传传递和进化遗传学的基本概念,包括多位点遗传、重组、哈迪-温伯格平衡和遗传漂变。这些学生一直要求有更多的演示和更多的练习题。考虑到这一需求,设计了“遗传学与进化”应用程序来帮助学生(及其教师),它提供了一套工具,使他们能够:(1)模拟具有不同基因数量和遗传模式的遗传杂交;(2)模拟自然选择和/或遗传漂变下的等位基因频率变化;(3)自我测试以强化术语(任何教师都可为整个班级定制);(4)解决各种问题(重组率、哈迪-温伯格平衡、遗传力、种群增长);(5)在所有这些领域生成实际上数量无限的练习题供他们自己尝试。虽然其中一些功能在其他地方也有,但其他工具无法即时生成新的练习题,也无法在学生每天随身携带的设备上实现这些多样的功能。