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非洲非医院环境下无全身麻醉的地方性甲状腺肿手术治疗

Surgical treatment of endemic goiter in a nonhospital setting without general anesthesia in Africa.

作者信息

Gil J, Rodríguez J M, Gil E, Balsalobre M D, Hernández Q, Gonzalez F M, García J A, Torregrosa N, Tortosa J A, Diallo A B, Parrilla P

机构信息

Surgery Department, Endocrine and GI Units, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain,

出版信息

World J Surg. 2014 Sep;38(9):2212-6. doi: 10.1007/s00268-014-2553-8.

Abstract

BACKGROUND

Endemic goiter remains a serious public health problem and 75 % of people affected live in underdeveloped countries where treatment is difficult for various reasons. The aim of this article is to report our experience in African countries with the management and surgical treatment of endemic goiter, performed in a nonhospital setting and without general anesthesia in the context of a collaborative development project by experienced endocrine surgeons.

METHODS

Fifty-six black African patients with a goiter were studied. Those in poor general health, the elderly, patients with either small goiters or clinical hyperthyroidism, and those presenting with an acute episode of malaria were excluded from the study. Cervical epidural anesthesia with spontaneous ventilation was used and a partial thyroidectomy was performed. The technique used, its immediate complications, and early and late follow-up were analyzed.

RESULTS

Surgery was performed on 31 patients with grades 3 and 4 goiter without mortality and a morbidity rate of 11.9 %, with 97 % of all complications being minor. There were no instances of dysphonia or symptomatic hypocalcemia and the mean stay was 1.57 days (range 1.25-1.93). Follow-up in the first year was 71 % and no case of severe or recurrent hypothyroidism was detected.

CONCLUSIONS

Surgery without general anesthesia performed in a nonhospital setting in underdeveloped countries in patients with goiter is a viable option with good results and low morbidity.

摘要

背景

地方性甲状腺肿仍然是一个严重的公共卫生问题,75%的患者生活在欠发达国家,由于各种原因,这些国家的治疗存在困难。本文旨在报告我们在非洲国家开展的地方性甲状腺肿管理与外科治疗经验,该治疗是在一个由经验丰富的内分泌外科医生参与的合作开发项目中,在非医院环境下且不使用全身麻醉进行的。

方法

对56例患有甲状腺肿的非洲黑人患者进行了研究。一般健康状况较差者、老年人、甲状腺肿较小或患有临床甲亢的患者以及出现疟疾急性发作的患者被排除在研究之外。采用颈段硬膜外麻醉并自主通气,实施甲状腺部分切除术。分析所采用的技术、其即刻并发症以及早期和晚期随访情况。

结果

对31例3级和4级甲状腺肿患者实施了手术,无死亡病例,发病率为11.9%,所有并发症中97%为轻微并发症。未出现声音嘶哑或有症状的低钙血症病例,平均住院时间为1.57天(范围1.25 - 1.93天)。第一年的随访率为71%,未检测到严重或复发性甲状腺功能减退病例。

结论

在欠发达国家的非医院环境中,对甲状腺肿患者实施不使用全身麻醉的手术是一种可行的选择,效果良好且发病率低。

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