• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

虹膜角膜内皮综合征：临床视角

Iridocorneal endothelial syndrome: clinical perspectives.

作者信息

Walkden Andrew, Au Leon

机构信息

Manchester Royal Eye Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

Centre for Ophthalmology and Vision Sciences, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK.

出版信息

Clin Ophthalmol. 2018 Apr 9;12:657-664. doi: 10.2147/OPTH.S143132. eCollection 2018.

DOI:10.2147/OPTH.S143132
PMID:29670326
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5898599/
Abstract

This article aims to review the clinical management strategies available for the rare iridocorneal endothelial syndrome. The different clinical variations as well as the imaging techniques available to aid diagnosis are discussed. We then present the evidence available to help the reader to understand how the condition can be managed medically and also the important surgical aspects of treatment. This involves raised intraocular pressure management in addition to the visual management options of partial or full thickness keratoplasty. We hope that this review provides an exhaustive but also succinct review of the literature available on what is a rare and difficult condition to treat.

摘要

本文旨在综述针对罕见的虹膜角膜内皮综合征可用的临床管理策略。文中讨论了不同的临床变异情况以及有助于诊断的现有成像技术。接着，我们提供相关证据，以帮助读者了解该病症如何进行药物治疗以及治疗过程中重要的手术方面。这包括除了部分或全层角膜移植的视力管理选项外，还涉及眼内压的控制。我们希望这篇综述能对关于这种罕见且难以治疗的病症的现有文献进行全面而简洁的回顾。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ce3/5898599/b28b459cbeb3/opth-12-657Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ce3/5898599/435d4b9f1295/opth-12-657Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ce3/5898599/5e495d88fd4d/opth-12-657Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ce3/5898599/ee49bb265bce/opth-12-657Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ce3/5898599/b28b459cbeb3/opth-12-657Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ce3/5898599/435d4b9f1295/opth-12-657Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ce3/5898599/5e495d88fd4d/opth-12-657Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ce3/5898599/ee49bb265bce/opth-12-657Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ce3/5898599/b28b459cbeb3/opth-12-657Fig4.jpg

相似文献

1
Iridocorneal endothelial syndrome: clinical perspectives.虹膜角膜内皮综合征：临床视角
Clin Ophthalmol. 2018 Apr 9;12:657-664. doi: 10.2147/OPTH.S143132. eCollection 2018.
2
The iridocorneal endothelial syndrome.虹膜角膜内皮综合征。
Surv Ophthalmol. 2018 Sep-Oct;63(5):665-676. doi: 10.1016/j.survophthal.2018.01.001. Epub 2018 Jan 11.
3
Iridocorneal Endothelial Syndrome虹膜角膜内皮综合征
4
Glaucoma associated with iridocorneal endothelial syndrome in 203 Indian subjects.203名印度受试者中与虹膜角膜内皮综合征相关的青光眼
PLoS One. 2017 Mar 10;12(3):e0171884. doi: 10.1371/journal.pone.0171884. eCollection 2017.
5
Bilateral iridocorneal endothelial (ICE) syndrome with microspherophakia.双侧虹膜角膜内皮（ICE）综合征伴小晶状体。
J Coll Physicians Surg Pak. 2011 Jun;21(6):374-5.
6
Cogan-Reese syndrome: image analysis with specular microscopy, optical coherence tomography, and ultrasound biomicroscopy.科根-里斯综合征：利用镜面显微镜、光学相干断层扫描和超声生物显微镜进行图像分析
Digit J Ophthalmol. 2019 May 31;25(2):26-29. doi: 10.5693/djo.02.2019.05.001. eCollection 2019.
7
Iridocorneal Endothelial Syndrome with Coexisting Macular Edema and Neurosensory Detachment: An Unusual Case Report.伴有黄斑水肿和神经感觉性脱离的虹膜角膜内皮综合征：一例罕见病例报告
J Curr Glaucoma Pract. 2021 Sep-Dec;15(3):149-152. doi: 10.5005/jp-journals-10078-1315.
8
Iridocorneal endothelial syndrome in Thai patients: clinical variations.泰国患者的虹膜角膜内皮综合征：临床变异
Arch Ophthalmol. 2000 Feb;118(2):187-92. doi: 10.1001/archopht.118.2.187.
9
Diagnosis and Management of Iridocorneal Endothelial Syndrome.虹膜角膜内皮综合征的诊断与管理
Biomed Res Int. 2015;2015:763093. doi: 10.1155/2015/763093. Epub 2015 Sep 16.
10
Unique variations and characteristics of iridocorneal endothelial syndrome in China: a case series of 58 patients.中国虹膜角膜内皮综合征的独特变异与特征：58例病例系列研究
Int Ophthalmol. 2018 Oct;38(5):2117-2126. doi: 10.1007/s10792-017-0712-2. Epub 2017 Oct 10.

引用本文的文献

1
Descemet's membrane endothelial keratoplasty in an eye with iridocorneal endothelial syndrome and rare association of corneal ectasia.虹膜角膜内皮综合征合并罕见角膜扩张的患眼中的后弹力层内皮角膜移植术
Ther Adv Ophthalmol. 2025 Aug 18;17:25158414251343968. doi: 10.1177/25158414251343968. eCollection 2025 Jan-Dec.
2
Long-term surgical outcomes of combined Ahmed glaucoma valve implantation and phacoemulsification with intraocular lens implantation for patients with glaucoma secondary to iridocorneal endothelial syndrome.虹膜角膜内皮综合征继发青光眼患者行联合 Ahmed 青光眼阀植入术和超声乳化白内障吸除术联合人工晶状体植入术的长期手术效果。
BMC Ophthalmol. 2024 Oct 31;24(1):476. doi: 10.1186/s12886-024-03740-y.
3

本文引用的文献

1
One-year result of XEN45 implant for glaucoma: efficacy, safety, and postoperative management.XEN45 植入物治疗青光眼的一年疗效、安全性和术后管理。
Eye (Lond). 2018 Feb;32(2):324-332. doi: 10.1038/eye.2017.162. Epub 2017 Sep 1.
2
Glaucoma associated with iridocorneal endothelial syndrome in 203 Indian subjects.203名印度受试者中与虹膜角膜内皮综合征相关的青光眼
PLoS One. 2017 Mar 10;12(3):e0171884. doi: 10.1371/journal.pone.0171884. eCollection 2017.
3
ICE-Syndrome: A Case Report of Implantation of a Microbypass Xen Gel Stent After DMEK Transplantation.
Retrocorneal membrane interception enhanced penetrating canaloplasty for patients with open angle glaucoma secondary to ICE syndrome.
角膜后膜截除增强穿透性房角切开术治疗 ICE 综合征继发开角型青光眼。
Int Ophthalmol. 2024 Sep 26;44(1):395. doi: 10.1007/s10792-024-03211-9.
4
Two-Step Iridocorneal Endothelial Syndrome Management: Endocapsular Intraocular Lens and Artificial Iris Followed by Descemet's Stripping Automated Endothelial Keratoplasty.两步式虹膜角膜内皮综合征治疗：囊内人工晶状体和人工虹膜植入后行Descemet膜剥除自动内皮角膜移植术
Case Rep Ophthalmol. 2023 Oct 27;14(1):583-590. doi: 10.1159/000534277. eCollection 2023 Jan-Dec.
5
PreserFlo Microshunt for the management of intraocular pressure elevation in iridocorneal endothelial syndrome.PreserFlo微型分流器用于治疗虹膜角膜内皮综合征引起的眼压升高。
Am J Ophthalmol Case Rep. 2023 Sep 22;32:101932. doi: 10.1016/j.ajoc.2023.101932. eCollection 2023 Dec.
6
Spokewise iridotomy combined with Descemet stripping automated endothelial keratoplasty in iridocorneal endothelial syndrome.在虹膜角膜内皮综合征中，扇形虹膜切开术联合Descemet膜剥除自动内皮角膜移植术。
Front Med (Lausanne). 2023 Jul 6;10:1187009. doi: 10.3389/fmed.2023.1187009. eCollection 2023.
7
Clinical Outcomes of the Intraocular Lens Injector and Busin Glide for Descemet Stripping Automated Endothelial Keratoplasty in Patients with Iridocorneal Endothelial Syndrome.虹膜角膜内皮综合征患者行Descemet膜剥除自动内皮角膜移植术中人工晶状体注射器和Busin滑子的临床结果
J Clin Med. 2023 Feb 26;12(5):1856. doi: 10.3390/jcm12051856.
8
Iris Nevus (Cogan-Reese) Syndrome Presenting with Zonular Dehiscence during Cataract Extraction.虹膜痣（科根-里斯）综合征在白内障摘除术中出现晶状体悬韧带断裂。
Case Rep Ophthalmol. 2022 Jun 9;13(2):435-440. doi: 10.1159/000524823. eCollection 2022 May-Aug.
9
Cornea thinning in two cases of ICE syndrome.两例 ICE 综合征患者的角膜变薄。
BMJ Case Rep. 2020 Sep 28;13(9):e236354. doi: 10.1136/bcr-2020-236354.
10
Histological observation of trabecular meshwork in a patient with Axenfeld-Rieger syndrome-a new theory for the mechanism of ectropion uvea in congenital glaucoma.Axenfeld-Rieger综合征患者小梁网的组织学观察——先天性青光眼虹膜外翻机制的新理论
Int J Ophthalmol. 2020 Jul 18;13(7):1167-1169. doi: 10.18240/ijo.2020.07.24. eCollection 2020.
ICE综合征：DMEK移植术后植入微旁路异种凝胶支架的病例报告
J Glaucoma. 2017 Feb;26(2):e103-e104. doi: 10.1097/IJG.0000000000000584.
4
Trabeculectomy with Mitomycin-C in Patients with Iridocorneal Endothelial Syndrome: A Case Series.丝裂霉素C辅助小梁切除术治疗虹膜角膜内皮综合征：病例系列
J Clin Diagn Res. 2016 May;10(5):NR05-6. doi: 10.7860/JCDR/2016/16506.7782. Epub 2016 May 1.
5
[Intraoperative optical coherence tomography in corneal and glaucoma surgical procedures].[角膜和青光眼手术中的术中光学相干断层扫描]
Ophthalmologe. 2016 Aug;113(8):646-50. doi: 10.1007/s00347-016-0320-y.
6
Early Clinical Results of a Novel Ab Interno Gel Stent for the Surgical Treatment of Open-angle Glaucoma.一种用于开角型青光眼手术治疗的新型内路凝胶支架的早期临床结果
J Glaucoma. 2016 Jul;25(7):e691-6. doi: 10.1097/IJG.0000000000000352.
7
Phacoemulsification combined with a new ab interno gel stent to treat open-angle glaucoma: Pilot study.超声乳化联合新型内路凝胶支架治疗开角型青光眼：初步研究。
J Cataract Refract Surg. 2015 Sep;41(9):1905-9. doi: 10.1016/j.jcrs.2015.01.019. Epub 2015 Oct 23.
8
Diagnosis and Management of Iridocorneal Endothelial Syndrome.虹膜角膜内皮综合征的诊断与管理
Biomed Res Int. 2015;2015:763093. doi: 10.1155/2015/763093. Epub 2015 Sep 16.
9
Boston Type 1 Keratoprosthesis for Iridocorneal Endothelial Syndromes.用于虹膜角膜内皮综合征的波士顿1型人工角膜
Cornea. 2015 Nov;34(11):1383-6. doi: 10.1097/ICO.0000000000000616.
10
Feasibility and Outcome of Descemet Membrane Endothelial Keratoplasty in Complex Anterior Segment and Vitreous Disease.Descemet膜内皮角膜移植术治疗复杂眼前段及玻璃体疾病的可行性与疗效
Cornea. 2015 Nov;34(11):1351-7. doi: 10.1097/ICO.0000000000000625.