Bouwhuis Carola B, van der Heijden-Maessen Hélène C, Boldingh Eric J K, Bos Cees F A, Lankhorst Guus J
Department of Pediatric Rehabilitation, Sophia Rehabilitation Center , The Hague/Delft , The Netherlands .
Disabil Rehabil. 2015;37(2):97-105. doi: 10.3109/09638288.2014.908961. Epub 2014 Apr 14.
This review presents an overview of the effectiveness of preventive and corrective surgical interventions to treat hip displacement in patients with severe cerebral palsy (CP).
A systematic literature search was applied to identify studies concerning surgical procedures in hip(sub)luxations in severe CP (GMFCS IV and V). A qualitative analysis and a best evidence synthesis were performed for soft tissue surgery and osteotomies.
The literature search identified 15 studies, all of which were observational. Five studies involved soft tissue surgery and 10 involved osteotomies. Only one study involving soft tissue surgery was of sufficient quality. Nine of the 10 studies involving osteotomies were of sufficient quality, including a total of 189 patients. The mean MP (migration percentage) at follow-up ranged from 6 to 29%. No relationship could be established between the effect of the surgical procedure and the patients' age or the duration of follow-up. The percentage of patients reporting pain decreased from 81% preoperatively to 5% at follow-up. Twenty-five percent had complications such as osteoarthritis, ulcers or fractures.
There is insufficient evidence for the effectiveness of soft tissue surgery to stabilize the hip, due to insufficient quality of the retrospective observational studies. This review shows indicative findings (provided by consistent, statistically significant findings on outcome and/or process measures in at least two Observational Studies with sufficient quality) for an effect of bony surgery in stabilizing the hip. Timing of the procedure remains an issue. Multicenter trials could shed further light on this complicated subject.
本综述概述了预防性和矫正性外科手术干预治疗重度脑瘫(CP)患者髋关节脱位的有效性。
采用系统文献检索,以确定有关重度CP(GMFCS IV和V级)髋关节(半)脱位手术程序的研究。对软组织手术和截骨术进行了定性分析和最佳证据综合分析。
文献检索确定了15项研究,均为观察性研究。5项研究涉及软组织手术,10项涉及截骨术。只有1项涉及软组织手术的研究质量足够。10项涉及截骨术的研究中有9项质量足够,共包括189例患者。随访时的平均MP(移位百分比)范围为6%至29%。手术效果与患者年龄或随访时间之间未发现关联。报告疼痛的患者百分比从术前的81%降至随访时的5%。25%的患者出现骨关节炎、溃疡或骨折等并发症。
由于回顾性观察性研究质量不足,尚无足够证据证明软组织手术稳定髋关节的有效性。本综述显示了骨手术在稳定髋关节方面有效果的指示性发现(至少两项质量足够的观察性研究在结局和/或过程指标上有一致的、具有统计学意义的发现)。手术时机仍然是一个问题。多中心试验可能会进一步阐明这个复杂的问题。