Takada Tomoya, Kurosaki Rei, Konno Yuji, Abe Shigeaki
J Nanosci Nanotechnol. 2014 Apr;14(4):3216-20. doi: 10.1166/jnn.2014.8590.
Effect of sidewall carboxylation on protein adsorption behavior of multi-walled carbon nanotubes (MWCNTs) was studied. Two water-soluble proteins, bovine serum albumin (BSA) and egg white lysozyme (LYS), were employed in this work. Carboxylation of MWCNTs suppressed adsorption of BSA, whereas adsorption of LYS was enhanced by the carboxylation. These behaviors are explained by the difference in the dominance of hydrophobic interaction and ionic interaction between MWCNTs and the proteins.
研究了侧壁羧基化对多壁碳纳米管（MWCNTs）蛋白质吸附行为的影响。本研究使用了两种水溶性蛋白质，即牛血清白蛋白（BSA）和蛋清溶菌酶（LYS）。MWCNTs的羧基化抑制了BSA的吸附，而LYS的吸附则因羧基化而增强。这些行为可以通过MWCNTs与蛋白质之间疏水相互作用和离子相互作用的主导差异来解释。
