Li Yi, Bao Fang Jun
North HuaShan Hospital, FuDan University , Shang Hai , PR China .
J Med Eng Technol. 2014 May;38(4):179-87. doi: 10.3109/03091902.2014.899401. Epub 2014 Apr 15.
The purpose of this study was to evaluate the interocular symmetry of several biometric parameters between both eyes. The symmetry between the right and left eye of 397 subjects in 14 biometric parameters, spherical equivalent of refractive error (SE), Jackson crossed cylinder power of refractive error astigmatism with axes at 90° and 180° (RJ0) and at 45° and 135° (RJ45), best-corrected visual acuity (BCVA), average corneal curvature (CC), Jackson crossed cylinder power of corneal astigmatism (CJ0 and CJ45), corneal asphericity coefficient (Q), intraocular pressure (IOP), central corneal thickness (CCT), axial length (AL), anterior chamber depth (ACD), lens thickness (LT) and vitreous chamber depth (VCD), was assessed by comparative data analysis. Aside from RJ0 (p = 0.00), RJ45 (p = 0.02) and Q (p = 0.00), the overall interocular differences of other biometric parameters between fellow eyes were not significant (p > 0.05). The interocular correlation and Bland-Altman plots showed a good agreement between fellow eyes in 14 biometric parameters. Correlations between interocular differences in SE and that in RJ0 (p = 0.03), CC (p = 0.00), AL (p = 0.00) and VCD (p = 0.00) were statistically significant. There were similar strong linear relationships between refractive error astigmatism vectors and corneal astigmatism vectors in bilateral eyes. There were negative correlations of RJ45 and CJ45 between bilateral eyes. A potentially clinically important interocular symmetry in SE, BCVA, CC, CJ0, CJ45, IOP, CCT, AL, ACD, LT and VCD is found in this research, while the differences of RJ0, RJ45 and Q between left and right eyes seem a bit large. The negative interocular relationships of RJ45 and CJ45 demonstrate moderate mirror symmetry exists among fellow eyes. High interocular symmetry in bilateral eyes may be helpful in intraocular lens power calculation, intraocular pressure evaluation, post-operative visual acuity and refraction prediction at the time the fellow eye is undergoing refractive surgery.
本研究的目的是评估双眼之间几个生物特征参数的眼间对称性。通过比较数据分析，评估了14个生物特征参数在397名受试者左右眼之间的对称性，这些参数包括等效球镜度（SE）、90°和180°轴向的屈光性散光的杰克逊交叉柱镜度数（RJ0）以及45°和135°轴向的（RJ45）、最佳矫正视力（BCVA）、平均角膜曲率（CC）、角膜散光的杰克逊交叉柱镜度数（CJ0和CJ45）、角膜非球面系数（Q）、眼压（IOP）、中央角膜厚度（CCT）、眼轴长度（AL）、前房深度（ACD）、晶状体厚度（LT）和玻璃体腔深度（VCD）。除RJ0（p = 0.00）、RJ45（p = 0.02）和Q（p = 0.00）外，其他生物特征参数在双眼之间的总体眼间差异不显著（p > 0.05）。眼间相关性和布兰德-奥特曼图显示，14个生物特征参数在双眼之间具有良好的一致性。SE的眼间差异与RJ0（p = 0.03）、CC（p = 0.00）、AL（p = 0.00）和VCD（p = 0.00）的眼间差异之间的相关性具有统计学意义。双眼的屈光性散光矢量和角膜散光矢量之间存在类似的强线性关系。双眼之间RJ45和CJ45呈负相关。本研究发现，在SE、BCVA、CC、CJ0、CJ45、IOP、CCT、AL、ACD、LT和VCD方面存在潜在具有临床重要性的眼间对称性，而左右眼之间RJ0、RJ45和Q的差异似乎有点大。RJ45和CJ45的眼间负相关表明双眼之间存在中度镜像对称。双眼的高眼间对称性可能有助于在对侧眼进行屈光手术时进行人工晶状体屈光度计算、眼压评估、术后视力和屈光预测。
