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英国曲马多的非医疗用途:来自大型社区样本的研究结果

The non-medical use of tramadol in the UK: findings from a large community sample.

作者信息

Winstock A R, Borschmann R, Bell J

机构信息

Kings Health Partners, Kings College London, London, UK; Insitute of Psychiatry, Kings College London, London, UK; Global Drug Survey, London, UK.

出版信息

Int J Clin Pract. 2014 Sep;68(9):1147-51. doi: 10.1111/ijcp.12429. Epub 2014 Apr 15.

Abstract

BACKGROUND

Prescription drug misuse has become a public health problem in several developed countries. In the UK, there has been no increase in people seeking treatment for prescription drug dependence, but there has been a progressive rise in fatal overdoses involving tramadol.

OBJECTIVES

To explore the source, motivations for use and patterns of use of tramadol in the UK.

METHODS

We conducted anonymous online survey of drug use and related behaviours as part of an ongoing drug trend monitoring initiative. We included questions assessing the patterns of use, source and function of tramadol.

RESULTS

UK Survey respondents (n = 7360) were predominantly young (mean age 29), and 90% reported being employed or studying. Less than 1% reported past-year use of heroin or methadone, but about 1/3 reported past-year use of cocaine. 326 (5% of respondents) reported having used tramadol in the preceding year, usually obtained by prescription but in 1/3 of cases from a friend; rarely from a dealer or from the internet. Most used the drug for pain relief, but 163 respondents (44%) reported using tramadol for reasons other than pain relief - particularly, using it to relax, to sleep, to get high or to relieve boredom. Nineteen per cent took doses higher than prescribed, and 10% reported difficulty discontinuing. Twenty-eight per cent combined tramadol with alcohol or other drugs to enhance its effect.

CONCLUSION

Misuse and sharing of tramadol, supplied by prescription, was common.

摘要

背景

在一些发达国家,处方药滥用已成为一个公共卫生问题。在英国,寻求处方药依赖治疗的人数并未增加,但涉及曲马多的致命过量用药情况却在逐渐上升。

目的

探讨英国曲马多的来源、使用动机和使用模式。

方法

作为一项正在进行的毒品趋势监测倡议的一部分,我们对药物使用及相关行为进行了匿名在线调查。我们纳入了评估曲马多使用模式、来源和作用的问题。

结果

参与英国调查的受访者(n = 7360)以年轻人为主(平均年龄29岁),90%的受访者表示有工作或在学习。不到1%的受访者报告过去一年使用过海洛因或美沙酮,但约1/3的受访者报告过去一年使用过可卡因。326人(占受访者的5%)报告在前一年使用过曲马多,通常是通过处方获得,但在1/3的情况下是从朋友处获得;很少从毒贩或互联网获取。大多数人使用该药物是为了缓解疼痛,但163名受访者(44%)报告使用曲马多并非出于缓解疼痛的原因——特别是为了放松、助眠、寻求快感或排解无聊。19%的人服用剂量高于规定剂量,10%的人报告停药困难。28%的人将曲马多与酒精或其他药物混合使用以增强效果。

结论

由处方提供的曲马多的滥用和共享情况很常见。

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