[老年性白内障患者角膜球差的分析]

[Analysis of the corneal spherical aberration in people with senile cataract].

作者信息

Yuan Li, Bao Yongzhen

机构信息

Department of Ophthalmology, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid diseases, People's Hospital, Peking University, Beijing 100044, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2014 Feb;50(2):100-4.

PMID:24735663

Abstract

OBJECTIVE

To investigate the distribution of the spherical aberration in people with senile cataract, in the interest of the customized selection of the intraocular lens in cataract surgeries and the future design of the intraocular lens.

METHODS

Retrospective study. Analysis of 922 eyes from 504 patients over 60-years-old was made. Patients were subdivided into 3 age groups (153 patients of 60-<70 years-old in group 1, 251 patients of 70-<80 years-old in group 2, 100 patients of 80- ≤ 90 years-old in group 3). Pentacam anterior segment analyzer (OCULUS, Germany) was used to measure the average corneal and posterior surface K-readings. The Zernike coefficients of corneal spherical aberration was calculated. The difference of corneal parameters among each age group was compared.

RESULTS

The average age of all patients was (73.5 ± 6.8) years-old. The average corneal K-reading was (44.50 ± 1.39)D and the average K-reading of corneal posterior surface was (-6.44 ± 0.25)D. There was no difference among 3 age groups (F = 0.738 and 0.373 retrospectively, P > 0.05). The corneal and posterior surface average K-readings had no correlation with the age. The average spherical aberration of anterior corneal surface was (0.361 ± 0.122)µm in group 1, (0.401 ± 0.139)µm in group 2 and (0.440 ± 0.145)µm in group 3 respectively. The spherical aberration of posterior corneal surface was (-0.122 ± 0.035)µm, (-0.105 ± 0.040)µm and (-0.090 ± 0.043)µm respectively. The total corneal spherical aberration was (0.360 ± 0.142)µm, (0.421 ± 0.158)µm and (0.476 ± 0.170)µm respectively. Significant differences were observed among 3 age groups (F = 10.561, 20.937 and 17.257 retrospectively, P < 0.01). The spherical aberrations of the corneal anterior, posterior surface and total cornea had positive correlation with the age (r = 0.203, 0.288 and 0.258 respectively, P < 0.01). The corneal spherical aberrations had no differences between right and left eyes, and had significant positive correlation between both sides.

CONCLUSIONS

The people with senile cataract over 60-year-old had higher corneal spherical aberrations than other age. The corneal spherical aberrations increased with the age and had significant correlation inter-ocularly.

摘要

目的

为了在白内障手术中进行人工晶状体的个性化选择以及未来人工晶状体的设计，研究老年性白内障患者的球差分布情况。

方法

回顾性研究。对504例60岁以上患者的922只眼进行分析。患者被分为3个年龄组（第1组153例60 - <70岁患者，第2组251例70 - <80岁患者，第3组100例80 - ≤90岁患者）。使用Pentacam眼前节分析仪（德国OCULUS公司）测量角膜和后表面的平均K值读数。计算角膜球差的泽尼克系数。比较各年龄组之间角膜参数的差异。

结果

所有患者的平均年龄为（73.5 ± 6.8）岁。角膜平均K值读数为（44.50 ± 1.39）D，角膜后表面平均K值读数为（-6.44 ± 0.25）D。3个年龄组之间无差异（回顾性分析F = 0.738和0.373，P > 0.05）。角膜和后表面平均K值读数与年龄无相关性。第1组、第2组和第3组角膜前表面平均球差分别为（0.361 ± 0.122）µm、（0.401 ± 0.139）µm和（0.440 ± 0.145）µm。角膜后表面球差分别为（-0.122 ± 0.035）µm、（-0.105 ± 0.040）µm和（-0.090 ± 0.043）µm。角膜总球差分别为（0.360 ± 0.142）µm、（0.421 ± 0.158）µm和（0.476 ± 0.170）µm。3个年龄组之间观察到显著差异（回顾性分析F = 10.561、20.937和17.257，P < 0.01）。角膜前表面、后表面和总角膜的球差与年龄呈正相关（r分别为0.203、0.288和0.258，P < 0.01）。角膜球差在右眼和左眼之间无差异，且两眼之间呈显著正相关。