Dekaken Aoulia, Gouri Adel, Bentorki Ahmed Aimen, Yakhlef Amina
Department of internal medicine and cardiology, El Okbi Hospital, Guelma, Algeria.
Laboratory of medical biochemistry, IBN Zohr Hospital, Guelma, Algeria.
Ann Biol Clin (Paris). 2014 Mar-Apr;72(2):245-8. doi: 10.1684/abc.2014.0934.
Primary hyperparathyroidism is a common endocrine disorder, asymptomatic and diagnosed through a fortuitous hypercalcemia. Brown tumors are exceptional but severe hyperparathyroidism bone complications. We report in this paper an original observation of hyperparathyroidism due to a parathyroid adenoma presenting as a brown tumor. A 28 year-old girl admitted for a bone tumor of the knee, the blood test shows hypercalcemia with hyperparathyroidism, bone biopsy revealed giant cell lesions characteristic of brown tumors.
原发性甲状旁腺功能亢进是一种常见的内分泌疾病,通常无症状,通过偶然发现的高钙血症得以诊断。棕色瘤是罕见但严重的甲状旁腺功能亢进骨并发症。我们在本文中报告了一例因甲状旁腺腺瘤导致甲状旁腺功能亢进并表现为棕色瘤的独特病例。一名28岁女孩因膝部骨肿瘤入院,血液检查显示高钙血症伴甲状旁腺功能亢进,骨活检发现具有棕色瘤特征的巨细胞病变。