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膝关节棕色瘤作为甲状旁腺腺瘤所致原发性甲状旁腺功能亢进的首发表现:一例报告

Brown tumor of the knee as the first presentation of primary hyperparathyroidism caused by parathyroid adenoma: A case report.

作者信息

Tapadia Vaishnavi C, Riyaz Romana, Shrestha Abhigan Babu, Ankolvi Javeed Akhtar

机构信息

Department of Radiology, Shadan Institute of Medical Sciences and Research, Hyderabad, Telanhana, India.

M Abdur Rahim Medical College, Dinajpur, Bangladesh.

出版信息

Radiol Case Rep. 2023 Mar 6;18(5):1852-1855. doi: 10.1016/j.radcr.2023.01.080. eCollection 2023 May.

DOI:10.1016/j.radcr.2023.01.080
PMID:36926540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10011679/
Abstract

Brown tumor of the knee is a focal benign cystic lesion of bone. The etiopathogenesis of brown tumor is believed to be abnormal bone metabolism in patients with hyperparathyroidism. We present a case of a 32-year-old male with recurrent knee pain, weakness of the lower limb and a nodular mass on left inferior lobe of thyroid. Timely identification of the underlying cause and localization of lesion(s) is important because the management and prognosis vary based on the etiology. The diagnosis of a brown tumor is the result of the sum of the medical history of patients with clinical, radiographic imaging, histopathological, hematological, and biochemical laboratory investigations.

摘要

膝关节棕色瘤是一种局限性骨良性囊性病变。棕色瘤的发病机制被认为是甲状旁腺功能亢进患者的骨代谢异常。我们报告一例32岁男性患者,有反复膝关节疼痛、下肢无力以及甲状腺左叶下极有一个结节状肿块。及时识别潜在病因和病变定位很重要,因为治疗和预后因病因不同而有所差异。棕色瘤的诊断是患者病史、临床检查、影像学检查、组织病理学检查、血液学检查和生化实验室检查结果综合判断的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b99/10011679/4600d2fa1580/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b99/10011679/4efb1cf37393/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b99/10011679/d51ec7e1d01a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b99/10011679/03fe9d8e2416/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b99/10011679/4600d2fa1580/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b99/10011679/4efb1cf37393/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b99/10011679/d51ec7e1d01a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b99/10011679/03fe9d8e2416/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b99/10011679/4600d2fa1580/gr4.jpg

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本文引用的文献

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Multiple Brown tumors in a Case of Primary Hyperparathyroidism with Pathological Fracture in Femur.原发性甲状旁腺功能亢进症合并股骨病理性骨折患者的多发棕色瘤
J Orthop Case Rep. 2020 Sep;10(6):49-53. doi: 10.13107/jocr.2020.v10.i06.1872.
2
Primary Hyperparathyroidism with Extensive Brown Tumors and Multiple Fractures in a 20-Year-Old Woman.20 岁女性原发性甲状旁腺功能亢进症伴广泛棕色瘤和多处骨折。
Endocrinol Metab (Seoul). 2015 Dec;30(4):614-9. doi: 10.3803/EnM.2015.30.4.614. Epub 2015 Sep 10.
3
Brown tumor of the patella caused by primary hyperparathyroidism: a case report.
原发性甲状旁腺功能亢进所致髌骨棕色瘤1例报告
Korean J Radiol. 2015 May-Jun;16(3):613-6. doi: 10.3348/kjr.2015.16.3.613. Epub 2015 May 13.
4
Brown tumor of the cervical spines: a case report with literature review.颈椎棕色瘤:一例病例报告并文献复习
Asian Spine J. 2015 Feb;9(1):110-20. doi: 10.4184/asj.2015.9.1.110. Epub 2015 Feb 13.
5
Brown tumor in a patient with ectopic mediastinal parathyroid adenoma: A case report.异位纵隔甲状旁腺腺瘤患者的棕色瘤:一例报告
Saudi Dent J. 2014 Apr;26(2):74-7. doi: 10.1016/j.sdentj.2013.12.009. Epub 2014 Mar 24.
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Brown tumors of the femur and pelvis secondary to a parathyroid carcinoma: report of one case.甲状旁腺癌继发股骨和骨盆棕色瘤1例报告
Rev Med Chil. 2014 Jul;142(7):919-23. doi: 10.4067/S0034-98872014000700014.
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Ann Biol Clin (Paris). 2014 Mar-Apr;72(2):245-8. doi: 10.1684/abc.2014.0934.
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Skeletal Radiol. 2014 May;43(5):693-7. doi: 10.1007/s00256-013-1770-9. Epub 2013 Nov 24.
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